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建立一种结构逼真的心肌细胞的有限元几何模型研究蜂窝结构在心肌系统生物学中的作用
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Creating a Structurally Realistic Finite Element Geometric Model of a Cardiomyocyte to Study the Role of Cellular Architecture in Cardiomyocyte Systems Biology
DOI:

08:54 min

April 18, 2018

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Chapters

  • 00:04Title
  • 01:19Segment Myofibrils and Mitochondria Regions from the EM 3D Image Dataset
  • 03:05Create a Finite Element Mesh from the Segmented Components
  • 04:36Mathematically Map the Spatially Varying Density of Ion-channels of Interest onto the Finite Element Mesh
  • 06:51Results: A Structurally Realistic Finite Element Geometric Model of a Cardiomyocyte
  • 08:13Conclusion

Summary

자동 번역

该协议概述了一种新的方法, 以建立一个空间详细的有限元模型的细胞内体系结构的电子显微镜和共焦显微图像。通过对钙信号和生物能学的案例研究, 证明了这个空间细节模型的威力。

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