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Un modelo de nervio ciático murinos In Vivo de invasión Perineural
JoVE 신문
암 연구학
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JoVE 신문 암 연구학
An In Vivo Murine Sciatic Nerve Model of Perineural Invasion
DOI:

09:55 min

April 23, 2018

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Chapters

  • 00:05Title
  • 01:25Preparation of Cultured Cancer Cells
  • 02:35Preparation of Mouse and Surgery
  • 06:06Sciatic Nerve Extraction
  • 07:24Nerve Processing and Quantification
  • 08:26Results: H&E Longitudinal Sections of Sciatic Nerves Injected with Panc02H7 Cancer Cells in Wild Type and NCAM KO Mice
  • 09:10Conclusion

Summary

자동 번역

Describimos un modelo murino en vivo de invasión perineural por células de cáncer pancreático syngeneic de inyección en el nervio ciático. El modelo permite la cuantificación del grado de invasión del nervio y apoya la investigación de los mecanismos celulares y moleculares de la invasión perineural.

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