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Journal / Cancer Research / Immunglobulin-gen-Sequenzanalyse In chronischer…
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Cancer Research

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JoVE Journal Cancer Research
Immunglobulin-gen-Sequenzanalyse In chronischer lymphatischer Leukämie
 
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Immunglobulin-gen-Sequenzanalyse In chronischer lymphatischer Leukämie: Aus Patientenmaterial Sequenz Interpretation

Article DOI: 10.3791/57787-v • 09:02 min • November 26th, 2018
November 26th, 2018 •
*1, *2,3, 1, 4, 5, 6, 7, 2,3, 1,2, 8
1Institute of Applied Biosciences, Centre for Research and Technology Hellas, 2Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 3Department of Molecular Medicine and Surgery, Karolinska Institutet, 4Division of Immunology, Transplantation and Infectious, IRCCS San Raffaele Scientific Institute, 5Department of Immunology, Laboratory for Medical Immunology, Erasmus University Medical Center, 6Hematology Department, Nikea General Hospital, 7Assistance publique - Hôpitaux de Paris (AP-HP), Hopital Pitié-Salpêtrière, Department of Hematology, and UPMC University Paris 06, UMRS 1138, 8Division of Experimental Oncology, IRCCS Istituto Scientifico San Raffaele and Università Vita-Salute San Raffaele
* These authors contributed equally

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Hier präsentieren wir eine Protokoll, das Details der technischen Aspekte und wesentliche Voraussetzungen, um robuste IG gen Sequenzanalyse bei Patienten mit chronischer lymphatischer Leukämie (CLL), stellen Sie sicher basierend auf den gesammelten Erfahrungen der Europäischen Forschungsinitiative auf CLL (ERIC).

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Cancer Research Ausgabe 141 chronischer lymphatischer Leukämie (CLL) somatische Hypermutation (SHM) Immunglobulin Immunglobulin schwere Variable (IGHV) Komplementarität die Bestimmung der Region 3 (CDR3) International Immungenetik-Informations-System (IMGT)
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