/

의학

/

猪自体移植肝细胞外细胞外细胞基因治疗

JoVE 신문
의학

JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.

JoVE 신문 의학

Lentiviral Vector-mediated Gene Therapy of Hepatocytes Ex Vivo for Autologous Transplantation in Swine

Please note that all translations are automatically generated. Click here for the English version.

猪自体移植肝细胞外细胞外细胞基因治疗

DOI:

10.3791/58399-v

•

09:54 min

•

November 04, 2018

•

Robert A. Kaiser², Shennen A. Mao, Jaime Glorioso, Bruce Amiot, Clara T. Nicolas, Kari L. Allen, Zeji Du, Caitlin J VanLith, Raymond D. Hickey, Scott L. Nyberg, Joseph B. Lillegard^2,4

¹Department of Surgery,Mayo Clinic, ²Midwest Fetal Care Center,Children’s Hospitals and Clinics of Minnesota, ³Department of Surgery,Johns Hopkins, ⁴Pediatric Surgical Associates

Chapters

00:04Title
01:22Laparoscopic Partial Hepatectomy
03:28Hepatocyte Isolation and Transplantation
07:24Results: Representative Lentiviral Vector-mediated Hepatocyte Liver Function Rescue
09:09Conclusion

Summary

자동 번역

本方案旨在描述猪肝细胞分离和体外基因传递, 通过自体细胞移植治疗代谢疾病模型。虽然这种特殊的模式具有独特的优势, 有利于成功的治疗, 但应用是解决其他疾病和适应症的相关基础。

Tags

Keywords: Lentiviral Vector Gene Therapy Hepatocytes Ex Vivo Autologous Transplantation Inborn Errors Of Metabolism Liver Disease Hereditary Tyrosinemia Type 1 Surgical Procedure Laparoscopic Technique Liver Resection

Article

Embed

플레이리스트에 추가

Usage Statistics

Related Videos

患者组织及基因传递考试前的体外培养

在犬体内的肌肉功能测定

在免疫缺陷小鼠的建立和传播人类视网膜母细胞瘤肿瘤

在癌症的生产和检测活性氧（ROS）的

一种新的手术方法气管内注射生物活性剂在胎鼠模型

新洲形成的助手依赖型腺病毒载体介导的基因转移对糖尿病小鼠肝

基质辅助重塑和修复软骨缺损的自体软骨细胞移植在兔模型

Steps for the Autologous Ex vivo Perfused Porcine Liver-kidney Experiment

供肝易地常温灌注机

常温<em>离体</em>肾脏的灌注肾的移植保护移植前

Read Article