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Developmental Biology

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JoVE Journal Developmental Biology
Assessment of Ultrastructural Neuroplasticity Parameters After In Utero Transduction of the Developing Mouse Brain and Spinal Cord
 

Assessment of Ultrastructural Neuroplasticity Parameters After In Utero Transduction of the Developing Mouse Brain and Spinal Cord

Article DOI: 10.3791/59084-v • 10:28 min • February 26th, 2019
February 26th, 2019 •
*1, *1, 1, 1, 1, 2, 1
1Department of Neuroanatomy and Molecular Brain Research, Ruhr University Bochum, 2Central Animal Facility of the Medical Faculty, Ruhr University Bochum
* These authors contributed equally

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요약
Automatic Translation

The combination of transmission electron microscopy and in utero transduction is a powerful approach for studying morphological changes in the fine ultrastructure of the nervous system during development. This combined method allows deep insights into changes in structural details underlying neuroplasticity with respect to their topographical representation.

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Ultrastructural Neuroplasticity Parameters In Utero Transduction Developing Mouse Brain Developing Spinal Cord High-resolution Images Macro-meso-micro-and Nanostructures Tissue Atlas Translational Therapeutic Potential Congenital Neurodegenerative Diseases Embryonic Stages In Utero Transduction Technique Mouse Species Surgical Training Electron Microscopic Imaging Adeno-associated Virus Type 1 Coating Fast Green Dye Embryonic Day 14.5 Pregnant Mouse
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