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Journal / Medicine / 使用缺氧/SU5416模型对小鼠的肺高血压进行诱导和特征…
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使用缺氧/SU5416模型对小鼠的肺高血压进行诱导和特征
 
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使用缺氧/SU5416模型对小鼠的肺高血压进行诱导和特征

Article DOI: 10.3791/59252-v • 07:10 min • June 3rd, 2020
June 3rd, 2020 •
1, 2, 1, 1
1Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, 2Phospholamban Foundation

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该协议描述了小鼠肺高血压（PH）的诱导，基于暴露于缺氧和VEGF受体拮抗剂的注射。动物在协议启动3周后出现PH和右心室（RV）肥大。介绍了模型的功能和形态特征。

Tags

医学， 问题 160， 缺氧， SU5416， 苏根， 肺高血压， PH， 右心室压力， 肺血管重塑， 右心室重塑
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