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Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography
 

Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography

Article DOI: 10.3791/59393-v 09:13 min April 28th, 2020
April 28th, 2020

챕터

요약

Unrestrained barometric plethysmography is used to quantify the pattern of breathing in awake mice. We show that 15 s segments under a standardized protocol display similar values to an extended duration of quiet breathing. This methodology also allows for the quantification of apnea and augmented breaths during the first hour in the chamber.

Tags

Keywords: Barometric Plethysmography Breathing Pattern Senescent Mice Unrestrained Noninvasive Calibration Gas Mixer Metabolic Analyzer Oxygen Carbon Dioxide
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