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Neuroscience

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Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
 

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Article DOI: 10.3791/59511-v 09:41 min July 19th, 2019
July 19th, 2019

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요약

Multiple sclerosis is an inflammatory demyelinating disease with no cure. Analysis of brain tissue provides important clues to understanding the pathogenesis of the disease. Here we discuss the methodology and downstream analysis of MS brain tissue collected through a unique rapid autopsy program in operation at the Cleveland Clinic.

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Keywords: Multiple Sclerosis Rapid Autopsy In Situ MRI Tissue Processing Cerebral Hemispheres Primary Motor Cortex Tissue Fixation Tissue Preservation Neuropathology Neurodegenerative Disease
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