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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
DOI:

09:37 min

August 15, 2019

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Chapters

  • 00:04Title
  • 00:48Beginning a Search in MARRVEL Based on Human Genes and Variants
  • 01:47Obtaining Information about Ortholog Candidate Genes in Model Organism Data in MARRVEL
  • 05:26Beginning a Search in MARRVEL Based on Model Organism Genes
  • 06:35Interpreting MARRVEL Human Genetics Outputs for a Gene and Variant Search
  • 07:21Results: Representative MARRVEL Search Output: TBX2
  • 08:45Conclusion

Summary

자동 번역

Here, we present a protocol to access and analyze many human and model organism databases efficiently. This protocol demonstrates the use of MARRVEL to analyze candidate disease-causing variants identified from next-generation sequencing efforts.

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