Waiting
로그인 처리 중...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Bioengineering / Human Neural Organoids for Studying Brain Cancer…
JoVE Journal
Bioengineering

이 콘텐츠 오픈 액세스로 구독없이 시청하실 수 있습니다.

JoVE Journal Bioengineering
Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases
 

Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases

Article DOI: 10.3791/59682-v • 09:36 min • June 28th, 2019
June 28th, 2019 •
*1, *2, 2, 3, 3, 4, 5, 4, 2
1Laboratory of Tumor Immunology, Translational Research Center in Onco-Hematology, Department of Internal Medicine Specialties, Faculty of Medicine, University of Geneva, 2Department of Pathology and Immunology, University Medical Center, University of Geneva, 3Laboratory of Toxicology and Therapeutic Drug Monitoring, Geneva University Hospitals, 4Tissue Engineering Laboratory, Hepia/HES-SO, University of Applied Sciences Western Switzerland, 5Laboratory of Experimental cell therapy, Department of Diagnostics, Geneva University Hospitals
* These authors contributed equally

챕터

요약
Automatic Translation

This study introduces and describes protocols to derive two specific human neural organoids as a relevant and accurate model for studying 1) human glioblastoma development within human neural organoids exclusively in humans and 2) neuron dopaminergic differentiation generating a three-dimensional organoid.

Tags

Keywords: Neural Organoids Brain Cancer Neurodegenerative Diseases Pluripotent Stem Cells Three-dimensional Culture Neurosphere Neural Induction ROCK Inhibitor Dual-SMAD Inhibition Glioblastoma Parkinson's Disease Regenerative Medicine Physiological Development Reproducibility
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter