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研究左心室反向改造由主动脉脱体在啮齿动物

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Studying Left Ventricular Reverse Remodeling by Aortic Debanding in Rodents

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研究左心室反向改造由主动脉脱体在啮齿动物

DOI:

10.3791/60036-v

•

07:26 min

•

July 14, 2021

•

Patricia Goncalves-Rodrigues*¹, Daniela Miranda-Silva*¹, Adelino F. Leite-Moreira, Inês Falcão-Pires

¹Unidade de Investigação Cardiovascular, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina,Universidade do Porto

Chapters

00:04Introduction
01:07Aortic Banding Preparation and Post-Operative Care
02:40Aortic Debanding
03:36Echocardiography (ECG)
05:26Results: Representative Echocardiographic, Pressure Volume, and Histological Assessments of Cardiac Structure and Function
06:38Conclusion

Summary

자동 번역

在这里，我们描述了在成熟的主动脉收缩模型中手术主动脉脱体的分步协议。这个过程不仅允许研究左心室反向改造和肥大回归背后的机制，而且还可以测试可能加速心肌恢复的新疗法方案。

Tags

Keywords: Left Ventricular Reverse Remodeling Aortic Debanding Rodents Myocardial Reverse Remodeling Cardiomyocytes Regression Isometric Functional Recovery Pressure Overload Aortic Stenosis Mechanical Ventilation Analgesia Aortic Banding Aortic Debanding

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