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Chapters
- 00:00Title
- 01:54Procedure
- 02:13Pre-operative Procedures
- 03:12Partial Hepatectomy to Remove 70% Liver Mass
- 05:38Post-operative Care
- 06:35Injection of Drug in Partially Hepatectomized Animals to induce Liver Failure
- 06:58Results
- 09:19Conclusion
The acute liver failure animal model developed in the current study presents a feasible alternative for the study of potential therapies. The current model employs the combined effect of physical and drug-induced hepatic injury and provides a suitable time window to study the potential of novel therapies.
