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Inductie van diffuus axonal hersenletsel bij ratten op basis van rotatieversnelling
JoVE 신문
신경과학
Author Produced
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JoVE 신문 신경과학
Induction of Diffuse Axonal Brain Injury in Rats Based on Rotational Acceleration
DOI:

06:14 min

May 09, 2020

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Chapters

  • 00:04Introduction
  • 00:45Preparing Rats for the Experimental Procedure
  • 01:11Procedure of Induction Diffuse Axonal Brain Injury
  • 01:54Measurement of Rotational Kinematics, Biomechanical Parameters
  • 02:32Evaluation of Neurological Severity Score after 48 hours
  • 03:08Brain Collection for Histological Examination after 48 hours
  • 04:02Immunohistochemical Staining
  • 04:16Results
  • 05:22Conclusion

Summary

자동 번역

Dit protocol valideert een betrouwbaar, gemakkelijk uit te voeren en reproduceerbaar knaagdiermodel van diffuus axonaal letsel (DAI) dat wijdverspreide schade aan witte stof veroorzaakt zonder schedelbreuken of kneuzingen.

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