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Analyse du phénotype squelettique d’un modèle murin de suppression conditionnelle de Stat3
 
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Analyse du phénotype squelettique d’un modèle murin de suppression conditionnelle de Stat3

Article DOI: 10.3791/61390-v • 08:42 min • July 3rd, 2020
July 3rd, 2020 •
*1, *2, 1, 1, 1, 1, 3, 1
1Center of Craniofacial Orthodontics, Department of Oral and Cranio-maxillofacial Science, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research center of Stomatology, 2Department of Stomatology, Dalian Medical University, 3The 2nd Dental Center, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research center of Stomatology
* These authors contributed equally

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요약
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Ce protocole décrit une méthode canonique pour comprendre les gènes critiques contrôlant l’activité osteoclast in vivo. Cette méthode utilise un modèle murin transgénique et certaines techniques canoniques pour analyser le phénotype squelettique.

Tags

Biologie Numéro 161 phénotype squelettique métabolisme osseux étiquetage ostéoclastes STAT3 souris transgéniques
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