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近红外光免疫疗法为小鼠模型的胸膜传播

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Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination

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近红外光免疫疗法为小鼠模型的胸膜传播

DOI:

10.3791/61593-v

•

05:39 min

•

February 09, 2021

•

Hirotoshi Yasui, Yuko Nishinaga, Shunichi Taki, Kazuomi Takahashi, Yoshitaka Isobe, Kazuhide Sato^2,3

¹Respiratory Medicine,Nagoya University Graduate School of Medicine, ²Nagoya University Institute for Advanced Research, ³B3-Unit, Advanced Analytical and Diagnostic Imaging Center (AADIC)/Medical Engineering Unit (MEU),Nagoya University Institute for Advanced Research

Chapters

00:05Introduction
00:31Pleural Dissemination Model Generation
01:44Bioluminescence (BLI) Measurement
03:02Near-Infrared Photoimmunotherapy (NIR-PIT)
04:08Results: Representative NIR-PIT Thoracic Mouse Tumor Treatment
05:13Conclusion

Summary

자동 번역

近红外光免疫疗法（NIR-PIT）是一种新兴的癌症治疗策略，利用抗体光吸收剂（IR700Dye）结合光和NIR光来破坏癌细胞。在这里，我们提出了一种方法，评估NIR-PIT的抗肿瘤作用，在小鼠模型的胸膜传播肺癌和恶性胸膜间皮瘤使用生物发光成像。

Tags

Near Infrared Photoimmunotherapy Pleural Dissemination Mouse Model Bioluminescence Imaging D-luciferin 690-nanometer Laser Light Dose

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