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Cancer Research

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JoVE Journal Cancer Research
Een Murine Ommaya Xenograft-model om direct-gerichte therapie van leptomeningeale ziekte te bestuderen
 
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Een Murine Ommaya Xenograft-model om direct-gerichte therapie van leptomeningeale ziekte te bestuderen

Article DOI: 10.3791/62033-v • 07:17 min • January 29th, 2021
January 29th, 2021 •
1,2, 3, 4, 4, 1, 5, 6, 7, 4, 2, 1,2
1Department of Neuro-Oncology, H. Lee Moffitt Cancer Center & Research Institute, 2Department of Tumor Biology, H. Lee Moffitt Cancer Center & Research Institute, 3Department of Comparative Medicine, University of South Florida, 4Department of Breast Oncology, H. Lee Moffitt Cancer Center & Research Institute, 5Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, 6Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, 7Department of Medical Oncology, Roswell Park Comprehensive Cancer Center

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Hier beschrijven we een murine xenograft model dat functioneel lijkt op een Ommaya reservoir bij patiënten. We ontwikkelden de Murine Ommaya om nieuwe therapieën te bestuderen voor de universeel fatale leptomeningeale ziekte.

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Kankeronderzoek Nummer 167 Leptomeningeale ziekte experimentele modellen muizenmodel Murine Ommaya reservoir
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