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JoVE Journal Cancer Research
Injection veineuse portale d’organoïdes du cancer colorectal pour étudier la métastase hépatique Stroma
 
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Injection veineuse portale d’organoïdes du cancer colorectal pour étudier la métastase hépatique Stroma

Article DOI: 10.3791/62630-v • 07:59 min • September 3rd, 2021
September 3rd, 2021 •
1,2,3,4, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2,5, 1,2, 2, 1,2, 6, 3,4,7, 3, 2, 1,2
1Adelaide Medical School, University of Adelaide, 2South Australian Health and Medical Research Institute (SAHMRI), 3Department of Pathology, Nagoya University Graduate School of Medicine, 4Division of Molecular Pathology, Center for Neurological Disease and Cancer, Nagoya University Graduate School of Medicine, 5Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 6Translational and Clinical Research Institute, Newcastle University, 7International Center for Cell and Gene Therapy, Fujita Health University

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L’injection veineuse portale d’organoïdes du cancer colorectal (CCR) génère des métastases hépatiques riches en stroma. Ce modèle murin de métastases hépatiques du CCR représente un outil utile pour étudier les interactions tumeur-stroma et développer de nouvelles thérapies dirigées par le stroma telles que les thérapies géniques médiées par le virus adéno-associé.

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Recherche sur le cancer numéro 175
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