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Journal / Neuroscience / 帕金森病的6-羟基多巴胺大鼠模型
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JoVE Journal Neuroscience
帕金森病的6-羟基多巴胺大鼠模型
 
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帕金森病的6-羟基多巴胺大鼠模型

Article DOI: 10.3791/62923-v • 08:10 min • October 27th, 2021
October 27th, 2021 •
1, 1, 1, 1, 1, 1
1Department of Psychology, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo

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6-羟基多巴胺（6-OHDA）模型已经使用了几十年，以推进对帕金森病的理解。在该协议中，我们展示了如何通过在内侧前脑束中注射6-OHDA来执行大鼠的单侧黑质纹状体病变，评估运动缺陷并使用步进测试预测病变。

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神经科学，第176期，
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