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Immunology and Infection

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JoVE Journal Immunology and Infection
Therapeutische evaluatie van fecale microbiotatransplantatie in een interleukine 10-deficiënt muismodel
 
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Therapeutische evaluatie van fecale microbiotatransplantatie in een interleukine 10-deficiënt muismodel

Article DOI: 10.3791/63350-v • 05:41 min • April 6th, 2022
April 6th, 2022 •
1,2, 1, 2, 1
1Division of Gastroenterology, Department of Internal Medicine, University of Texas Medical Branch at Galveston, 2Department of Gastroenterology, Xiangya Hospital of Central South University

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De interactie van genetische gevoeligheid, mucosale immuniteit en intestinale micro-ecologische omgeving is betrokken bij de pathogenese van inflammatoire darmziekte (IBD). In deze studie pasten we fecale microbiota-transplantatie toe op IL-10-deficiënte muizen en onderzochten we de impact ervan op darmontsteking en hartfunctie.

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Immunologie en infectie Nummer 182 inflammatoire darmziekte fecale microbiotatransplantatie colitis ulcerosa ziekte van Crohn dysbiose interleukine 10
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