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1Eye Clinic, Department of Ophthalmology,University Hospital Giessen and Marburg GmbH, 2Karl Landsteiner Institute for Retinal Research and Imaging, 3Department of Ophthalmology, University Hospital Kralovske Vinohrady and Third Faculty of Medicine,Charles University in Prague, 4Institute of Macromolecular Chemistry,Czech Academy of Sciences, 5Institute of Animal Physiology and Genetics,Czech Academy of Sciences, 6Department of Cell Biology, Faculty of Science,Charles University, 7Institute of Experimental Medicine,Czech Academy of Sciences, 8Center for Eye Research, Department of Ophthalmology, Oslo University Hospital and Institute of Clinical Medicine, Faculty of Medicine,University of Oslo, 9Moorfields Eye Hospitals UAE, 10Stem Cell Therapies in Neurodegenerative Diseases Lab,Research Center “Principe Felipe”, 11Eye Center Donaustadt, Department of Ophthalmology,Sigmund Freud University
Chapters
- 00:00Introduction
- 01:53Surgical Procedure
- 06:42Enucleation of the Eye Post Mortem After Euthanasia
- 08:08Representative Results
- 09:53Conclusions
Die subretinale Implantation von retinalem Pigmentepithel (RPE) ist einer der vielversprechendsten Ansätze zur Behandlung degenerativer Netzhauterkrankungen. Die Leistung präklinischer Studien an großäugigen Tiermodellen bleibt jedoch eine Herausforderung. In diesem Bericht werden Leitlinien für die subretinale Transplantation von RPE auf einem Zellträger in Minischweine vorgestellt.
