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JoVE Journal Medicine
Forbedret gnavermodel af myokardieiskæmi og reperfusionsskade
 
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Forbedret gnavermodel af myokardieiskæmi og reperfusionsskade

Article DOI: 10.3791/63510-v • 07:23 min • March 7th, 2022
March 7th, 2022 •
*1,2,3, *3, 3, 4, 5, 3, 5, 6, 1,2, 7
1Department of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, 2Department of Cardiology, Jiangsu Province Hospital of Chinese Medicine, 3First College of Clinical Medicine, Biological Technology Center for Innovation in Chinese Medicine, Nanjing University of Chinese Medicine, 4School of Health Preservation and Rehabilitation, Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, 5Department of Cardiology, Jiangsu Provincial Hospital of Chinese Medicine, 6Department of Cardiology, Yancheng TCM Hospital Affiliated to Nanjing University of Chinese Medicine, 7Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine (TCM) Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine
* These authors contributed equally

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Myokardieiskæmi-reperfusionsmodel af rottehjerte forbedres ved hjælp af en selvfremstillet retraktor, polyvinylchloridrør og en unik knudemetode. Elektrokardiogram, triphenyltetrazoliumchlorid og histologisk farvning og procentvise overlevelsesanalyseresultater viste, at den forbedrede modelgruppe har højere succes- og overlevelsesrater end den allerede eksisterende modelgruppe.

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