췌장암을 모델링하기 위한 Syngeneic Mouse Orthotopic Allografts

Article DOI: 10.3791/64253-v • 06:20 min • October 4th, 2022

October 4th, 2022 •

Constantin Schmitt^1,2,3, Dieter Saur^1,2,3,4, Stefanie Bärthel*^1,2,3, Chiara Falcomatà*^1,2,3

¹Division of Translational Cancer Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), ²Translational Cancer Research and Institute of Experimental Cancer Therapy, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, ³Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, ⁴Department of Internal Medicine II, Klinikum rechts der Isar, Technical University of Munich

* These authors contributed equally

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췌관 선암종(PDAC)의 Syngeneic mouse orthotopic 동종이식편은 질병 아형의 생물학, 표현형 및 치료 반응을 요약합니다. 빠르고 재현 가능한 종양 진행으로 인해 전임상 연구에 널리 사용됩니다. 여기에서는 syngeneic murine PDAC 배양을 췌장에 주입하여 이러한 모델을 생성하는 일반적인 방법을 보여줍니다.

췌장암을 모델링하기 위한 Syngeneic Mouse Orthotopic Allografts

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