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면역학 및 감염병학

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鼻自组装纳米乳肿瘤疫苗体外和体内的制备、特性、毒性及疗效评价

JoVE 신문
면역학 및 감염병학

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JoVE 신문 면역학 및 감염병학

Preparation, Characteristics, Toxicity, and Efficacy Evaluation of the Nasal Self-Assembled Nanoemulsion Tumor Vaccine In Vitro and In Vivo

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鼻自组装纳米乳肿瘤疫苗体外和体内的制备、特性、毒性及疗效评价

DOI:

10.3791/64299-v

•

07:33 min

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September 28, 2022

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Zelong Zhang, Dingyi Cai, Shuang Ge, Xing Luo, Xiaoqiang Zeng, Yan Ye, Zhen Song, Liusheng Peng, Haibo Li, Quanming Zou, Hao Zeng, Hongwu Sun, Yun Yang

¹National Engineering Research Centre of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy,Third Military Medical University of Chinese PLA

Chapters

00:04Introduction
00:49Preparation of the I‐OVA NE
01:33In Vitro and In Vivo Toxicity Assays
05:25Results: In Vitro and In Vivo Experimental Evaluation of the Nasal Tumor Nanovaccine Delivery
07:06Conclusion

Summary

자동 번역

在这里，我们提出了鼻自组装纳米乳肿瘤疫苗体外和体内制备和评价的详细方法。

Tags

Keywords: Nasal Self-assembled Nanoemulsion Tumor Vaccine In Vitro In Vivo Monophosphorol Lipid A DMSO TWEEN 80 I-OVA Squalene MPLA BEAS2B Epithelial Cells PBS Trypsin RPMI 1640

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