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Coronavirus / COVID-19 Procedures
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JoVE 과학 교육 Coronavirus / COVID-19 Procedures
COVID-19 / Coronavirus Outbreak: How To Perform A Bronchoscopy

COVID-19 / 冠状病毒爆发:如何进行支气管镜检查

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개요

在大流行时期,医务人员正在成为对抗感染的关键资源。为了获得最佳的医疗服务,必须向医务人员传授相关的技术和程序,同时降低感染风险。COVID患者经常患有呼吸不全和肺内分泌增加。支气管镜检查是解决重症监护医学中呼吸道阻塞的标准程序之一。不利的一面是,由于呼吸机管断开,这种程序具有产生气溶胶形成的巨大潜力,这增加了医务人员的感染风险。支气管镜检查的适应症应限制在绝对最小值。此视频提供了在进行支气管镜检查时在不忽视患者安全的情况下降低个人感染风险的指南。

Procedure

进行支气管镜检查的适应症必须非常严格,即吸入分泌物、打开电位或气道堵塞的情况下。它不应作为COVID-19患者的常规程序用于诊断目的或收集样品。 在进入患者室之前,应准备和测试所有材料。 唐个人防护装备(长袍、帽子、护目镜、手套)和用于使用露天通道的其他装备:FFP3 / N-95 面罩、遮阳板、第二副手套。 如果可能,向患者解释流程并征得他们的同意。 检查血动力监测并激活监视器的 QRS 声音。 使用 FiO2 1.0 预氧。 调整手术的呼吸机参数(即音量控制的通风),包括报警设置。 检查吸气装置并连接指尖接头。 将支气管镜放在对面的床边,以确保可直接查看监视器。 不要穿无菌的长袍和手套,在病人上盖上无菌的防护罩。手术应尽可能无菌地进行,以避免细菌性肺感染。 准备所需的材料,并把它们放在无菌区域。准备支气管镜,将吸管连接到支气管镜,并在吸管镜之间设置分泌陷阱,并在微型喷头上用0.9%的NaCl填充三个20mL注射器。 引入或加深麻醉,并考虑肌肉放松。 停止整个团队:遵循 10 秒 10 分钟的原则(讨论问题、意见、事实、计划)。 插入带双手套的咬合器,插入后取下外手套。 在支气管镜上涂抹润滑剂和防雾剂。 停止呼吸机,让助手将气管放在位上。 更改为支气管镜角度片,并将支气管镜插入角度片和呼吸管。 开始通风。 前进支气管镜,同时定向到气管支撑环,并检查两个肺一个。应注意接触粘膜、分泌物和血液的脆弱性。如有必要,可以调动和吸吸分泌物以优化视图。 要执行支气管熔岩,请将 10mL 的 0.9% NaCl 插入深呼吸道,并将熔岩吸入分泌陷阱,以进行进一步诊断。如果需要更多探头,必须密封和交换分泌陷阱。 检查完成后,停止呼吸机。 拆下支气管镜并重新连接关闭的吸气装置。 在开始通风之前,请检查呼吸管的连接。 开始通风,执行招聘操作以减少进一步,并调整呼吸机设置。 进行肺声检查或胸部X光检查,以排除肺炎球类等并发症。 处理材料,让样品收集器准备好转移到实验室进行进一步诊断。

Disclosures

No conflicts of interest declared.

내레이션 대본

The indication for bronchoscopy in COVID-19 patients has to be strictly defined and should only be performed in case of, for example, aspirations, atelectasis, or relocation of the airways–not routinely for diagnostic purposes.

Minimize the team to essential personnel only. Normally, this would consist of one examiner and two assistants. All required equipment should be prepared outside of the patient’s room. A single-use only bronchoscope and appropriate monitor should be utilized with infected patients.

Enter the patient’s room wearing personal protective equipment. This includes a FFP3 mask, protective glasses and visor, and doubled-up gloves. Gain consent from the patient by explaining the procedure being undertaken.

All vital signs are to be continuously and appropriately monitored. The ECG trace loudspeaker is to be switched on. The patient will be pre-oxygenated with an FI02 of 1.0. This should additionally be carried out in patients receiving extracorporeal membrane oxygenation therapy treatment.

The ventilator settings are now to be adapted. Generally, a volume-controlled ventilation mode with appropriate alarms and pressure limits is selected. The suction catheter is to be turned on and the fingertip piece closed.

The video bronchoscope monitor must be placed directly opposite and in front of the examiner. Bronchoscopy is carried out under aseptic or hygienic conditions. A pair of sterile gloves and a sterile gown are to be laid out. Under these exceptional circumstances, the sterile zone must be prepared directly on the anesthetized patient. Finally, all sterile equipment should be placed in the sterile zone.

The single-use bronchoscope will now be prepared for usage. This, in turn, is attached to the monitor by an assistant. The suction catheter is connected to the specimen collector and, in turn, to the bronchoscope’s suction port.

Finally, the system is tested. Three 20-milliliter lavage syringes are to be filled with 0.9 percent sodium chloride under sterile conditions and laid to the side. Immediately following, the patient will be put into a deeper anesthetic state, including neuromuscular blockade.

Before beginning the procedure, the team will follow a 10 second for 10 minute principle, whereby facts, procedural planning, potential complications, and team roles can be clarified, and outstanding questions can be answered. The procedure may begin once everything is clarified.

An assistant, whilst wearing two sets of gloves, positions the bite block. A side piece of the bite block is cut in order to prevent endotracheal tube dislocation. The first pair of gloves are then removed and disposed of. Anti-fog is sprayed on the bronchoscope tip and water-soluble lubricant over the bronchoscope insertion tube.

The ventilator function is paused in order to begin the bronchoscopy. This is clearly verbally communicated with the team. The closed suction system is detached and replaced with an adapted bronchoscope valve. The small cover flap of the adapted bronchoscope valve is now opened.

An assistant holds the endotracheal tube in orientation to the patient’s midline. This must be held for the entire procedure. The bronchoscope is inserted through the open adapted bronchoscope valve into the endotracheal tube.  Here, it is advanced further.

The endotracheal tube is flushed and is secretion mobilized and subsequently suctioned. The bronchoscope may now be advanced further following clearance of any secretion. Once the carina is visualized, orientation of the bronchoscope with respect to the tracheal cartilage can be achieved, as seen in this video. 

Here, we can see that the right lung has a buildup of secretion. This must be lavaged and suctioned before the lung can be further examined. Now, the passage is free. The carina can be viewed, and the right lung may be examined. We can orientate the bronchoscope image easily, once again, with respect to the anteriorly positioned tracheal cartilage.

Step by step, we examine the early branching right upper lobe, the right middle lobe, and the right lower lobe. The visual status of the mucous membrane, its vulnerability, any secretion, and/or bleeding must be assessed. The mucous membrane is often very fragile in COVID-19 patients. Pus is to be expected, especially in case of a superinfection of bacteria.

When required, a deep bronchoalveolar lavage may be carried out with 10 milliliters of 0.9% sodium chloride. A 30 seconds delay should be carried out prior to performing intermittent suction with short intervals until the specimen collector is filled with 10 milliliters of aspirate.

Here, this is performed in the right lung. Lavage to be separated by lung lobes and separate specimen collectors are respectively used. During the exchange of specimen collectors, it’s important to minimize any aerosolization of aspirate. The connectors are detached initially from the suction catheter, then the bronchoscope, and these are in turn connected to each other.

In COVID-19 patients, three rather than two specimen collectors should be acquired in order to aid diagnosis. The left lung will now be examined, beginning from the carina. The left lobes of the lung are also sequentially examined.

Here is the upper lobe, and finally, the lower lobe. Bronchoalveolar lavage is also carried out. To obtain specimens for cytology, a third lavage can be taken. Finally, the bronchoscope is to be reversed out of the left lung. At this point, as during the entire procedure, it is important to monitor the fragility of the mucous membranes through contact. This often occurs in viral infections, including COVID-19.

Now, the bronchoscope is reversed and the position of the endotracheal tube confirmed. The ventilator is paused in order to finish the bronchoscopy procedure. The bronchoscope is now removed from the endotracheal tube. The adapted bronchoscope valve is exchanged with a closed suction system. All connections in the ventilation circuit are to be checked.

Finally, the ventilator is switched on, and if necessary, the ventilator settings are adapted. The specimen collectors are now closed with a white top marked with laboratory stickers and placed in a marked bag to be sent, in turn, to virology and to microbiology. The single-use bronchoscope and all remaining materials are to be disposed of.

Thank you very much.

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Cite This
JoVE Science Education Database. JoVE Science Education. COVID-19 / Coronavirus Outbreak: How To Perform A Bronchoscopy. JoVE, Cambridge, MA, (2020).