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Journal / Neuroscience / 使用轻度创伤性脑损伤的清醒闭合性头部损伤模型评估突触可塑性的变化…
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JoVE Journal Neuroscience
使用轻度创伤性脑损伤的清醒闭合性头部损伤模型评估突触可塑性的变化
 
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使用轻度创伤性脑损伤的清醒闭合性头部损伤模型评估突触可塑性的变化

Article DOI: 10.3791/64592-v • 09:49 min • January 20th, 2023
January 20th, 2023 •
1,2, 1, 1, 1, 1, 1, 1, 1, 1
1Division of Medical Sciences, University of Victoria, 2Island Medical Program, University of British Columbia

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在这里，展示了如何使用清醒闭合性头部损伤模型来检查反复轻度创伤性脑损伤（r-mTBI）对海马突触可塑性的影响。该模型在患者中复制了r-mTBI的重要特征，并与 体外 电生理学结合使用。

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神经科学，第191期，
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