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Journal / Cancer Research / 3Dオルガノイドによる口腔食道扁平上皮癌のモデリング…
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JoVE Journal Cancer Research
3Dオルガノイドによる口腔食道扁平上皮癌のモデリング
 
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3Dオルガノイドによる口腔食道扁平上皮癌のモデリング

Article DOI: 10.3791/64676-v • 10:43 min • December 23rd, 2022
December 23rd, 2022 •
*1, *1,2, 1, 1, 1, 1, 1, 1,3, 1,3, 4, 1,2, 1,5, 1,6, 1,7, 1,5, 1,2,5
1Herbert Irving Comprehensive Cancer Center, Columbia University, 2Organoid and Cell Culture Core, Columbia University Digestive and Liver Diseases Research Center, Columbia University, 3Department of Otolaryngology, Head and Neck Surgery, Columbia University, 4Histopathology Facility, Fox Chase Cancer Center, 5Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, 6Department of Genetics and Development, Columbia University, 7Section of Oral, Diagnostic and Rehabilitation Sciences, College of Dental Medicine, Columbia University
* These authors contributed equally

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このプロトコルでは、化学的発がんによって誘発される正常、腫瘍前、および扁平上皮がんの病変を表すマウスの口腔食道3Dオルガノイドを生成および特性評価するための重要なステップについて説明します。

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がん研究、第190号、
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