Francesca Chiodi Department of Microbiology, Tumor and Cell Biology Karolinska Institutet Biography Publications Institution JoVE Articles Francesca Chiodi has not added a biography. If you are Francesca Chiodi and would like to personalize this page please email our Author Liaison for assistance. Publications Bacterial Microbiome and Host Inflammatory Gene Expression in Foreskin Tissue Heliyon. Nov, 2023 | Pubmed ID: 38053902 Challenge Models for Infectious Diseases Critical Reviews in Microbiology. Nov, 2023 | Pubmed ID: 37909097 Evaluation of a Human Mucosal Tissue Explant Model for SARS-CoV-2 Replication PloS One. 2023 | Pubmed ID: 37769001 Dose Finding Study for On-demand HIV Pre-exposure Prophylaxis for Insertive Sex in Sub-Saharan Africa: Results from the CHAPS Open Label Randomised Controlled Trial EBioMedicine. Jul, 2023 | Pubmed ID: 37327677 A Randomized Clinical Trial of On-demand Oral Pre-exposure Prophylaxis Does Not Modulate Lymphoid/myeloid HIV Target Cell Density in the Foreskin AIDS (London, England). Sep, 2023 | Pubmed ID: 37289572 Proteomic Analysis of Mucosal and Systemic Responses to SARS-CoV-2 Antigen Vaccines. Feb, 2023 | Pubmed ID: 36851212 Women for Science and Science for Women: Gaps, Challenges and Opportunities Towards Optimizing Pre-exposure Prophylaxis for HIV-1 Prevention Frontiers in Immunology. 2022 | Pubmed ID: 36561760 Short-term Oral Pre-exposure Prophylaxis Against HIV-1 Modulates the Transcriptome of Foreskin Tissue in Young Men in Africa Frontiers in Immunology. 2022 | Pubmed ID: 36479111 Mobilization of Systemic CCL4 Following HIV Pre-exposure Prophylaxis in Young Men in Africa Frontiers in Immunology. 2022 | Pubmed ID: 35967369 Impaired CD4+ T Cell Differentiation in HIV-1 Infected Patients Receiving Early Anti-retroviral Therapy Genomics. May, 2022 | Pubmed ID: 35429609 Undetectable Anti-HBs Antibodies: Need of a Booster Dose for HIV-1-Infected Individuals Vaccines. Dec, 2021 | Pubmed ID: 34960230 Distinct Transcriptomic Profiles of Naïve CD4+ T Cells Distinguish HIV-1 Infected Patients Initiating Antiretroviral Therapy at Acute or Chronic Phase of Infection Genomics. Nov, 2021 | Pubmed ID: 34425224 Publisher Correction To: Direct Contact Between Plasmodium Falciparum and Human B-cells in a Novel Co-culture Increases Parasite Growth and Affects B-cell Growth Malaria Journal. Jul, 2021 | Pubmed ID: 34301260 Direct Contact Between Plasmodium Falciparum and Human B-cells in a Novel Co-culture Increases Parasite Growth and Affects B-cell Growth Malaria Journal. Jul, 2021 | Pubmed ID: 34225761 The Role of CXCL13 in Antibody Responses to HIV-1 Infection and Vaccination Frontiers in Immunology. 2021 | Pubmed ID: 33732259 Oncogenic Effects of HIV-1 Proteins, Mechanisms Behind Cancers. Jan, 2021 | Pubmed ID: 33467638 High CD45 Expression of CD8+ and CD4+ T Cells Correlates with the Size of HIV-1 Reservoir in Blood Scientific Reports. Nov, 2020 | Pubmed ID: 33235273 Profiling of Inflammatory Proteins in Plasma of HIV-1-Infected Children Receiving Antiretroviral Therapy Proteomes. Sep, 2020 | Pubmed ID: 32906648 Nasopharyngeal Carriage Among PCV-10-Vaccinated HIV-1-Infected Children with Maintained Serological Memory in Ethiopia Pathogens (Basel, Switzerland). Feb, 2020 | Pubmed ID: 32106620 Early Antiretroviral Therapy May Preserve Vaccine Responses in Human Immunodeficiency Virus-Infected Patients by Preventing Damage to Long-Lived Plasma Cells The Journal of Infectious Diseases. Jun, 2020 | Pubmed ID: 31867631 Impact of Chemokine C-C Ligand 27, Foreskin Anatomy and Sexually Transmitted Infections on HIV-1 Target Cell Availability in Adolescent South African Males Mucosal Immunology. Jan, 2020 | Pubmed ID: 31619762 Homing Defects of B Cells in HIV-1 Infected Children Impair Vaccination Responses Vaccine. Apr, 2019 | Pubmed ID: 30914222 Mass Cytometry Identifies Distinct CD4+ T Cell Clusters Distinguishing HIV-1-infected Patients According to Antiretroviral Therapy Initiation JCI Insight. Feb, 2019 | Pubmed ID: 30728327 DNA Immunization Site Determines the Level of Gene Expression and the Magnitude, but Not the Type of the Induced Immune Response PloS One. 2018 | Pubmed ID: 29864114 Editorial: HIV-Induced Damage of B Cells and Production of HIV Neutralizing Antibodies Frontiers in Immunology. 2018 | Pubmed ID: 29515590 Hepatitis B Virus Vaccination in HIV-1-Infected Young Adults: A Tool to Reduce the Size of HIV-1 Reservoirs? Frontiers in Immunology. 2017 | Pubmed ID: 29375579 T Follicular Helper Cells and Antibody Response to Hepatitis B Virus Vaccine in HIV-1 Infected Children Receiving ART Scientific Reports. Aug, 2017 | Pubmed ID: 28827754 IL-7 and CD4 T Follicular Helper Cells in HIV-1 Infection Frontiers in Immunology. 2017 | Pubmed ID: 28473831 Dendritic Cell Response to HIV-1 Is Controlled by Differentiation Programs in the Cells and Strain-Specific Properties of the Virus Frontiers in Immunology. 2017 | Pubmed ID: 28348557 Impaired B Cells Survival Upon Production of Inflammatory Cytokines by HIV-1 Exposed Follicular Dendritic Cells Retrovirology. Sep, 2016 | Pubmed ID: 27596745 Pneumococcal Vaccination of HIV-infected Young Adults is an Important Global Priority AIDS (London, England). Jul, 2016 | Pubmed ID: 27428577 Dysfunctional Phenotypes of CD4+ and CD8+ T Cells Are Comparable in Patients Initiating ART During Early or Chronic HIV-1 Infection Medicine. Jun, 2016 | Pubmed ID: 27281071 Dysfunctions in the Migratory Phenotype and Properties of Circulating Immature Transitional B Cells During HIV-1 Infection AIDS (London, England). Sep, 2016 | Pubmed ID: 27281060 Increased Extrafollicular Expression of the B-cell Stimulatory Molecule CD70 in HIV-1-infected Individuals AIDS (London, England). Sep, 2015 | Pubmed ID: 26262581 Impaired Phenotype and Function of T Follicular Helper Cells in HIV-1-Infected Children Receiving ART Medicine. Jul, 2015 | Pubmed ID: 26166114 Frequency and Phenotype of B Cell Subpopulations in Young and Aged HIV-1 Infected Patients Receiving ART Retrovirology. Sep, 2014 | Pubmed ID: 25213015 B-cell Responses After Intranasal Vaccination with the Novel Attenuated Bordetella Pertussis Vaccine Strain BPZE1 in a Randomized Phase I Clinical Trial Vaccine. Jun, 2014 | Pubmed ID: 24793938 Toll-like Receptor 3 Signalling Up-regulates Expression of the HIV Co-receptor G-protein Coupled Receptor 15 on Human CD4+ T Cells PloS One. 2014 | Pubmed ID: 24558379 Impairment of B-cell Functions During HIV-1 Infection AIDS (London, England). Sep, 2013 | Pubmed ID: 23595152 Relation of Activation-induced Deaminase (AID) Expression with Antibody Response to A(H1N1)pdm09 Vaccination in HIV-1 Infected Patients Vaccine. Apr, 2013 | Pubmed ID: 23499520 Concerted Effect of Lymphopenia, Viraemia and T-cell Activation on Fas Expression of Peripheral B Cells in HIV-1-infected Patients AIDS (London, England). Jan, 2013 | Pubmed ID: 23238551 IL-7 Modulates B Cells Survival and Activation by Inducing BAFF and CD70 Expression in T Cells Journal of Autoimmunity. Jun, 2012 | Pubmed ID: 22341853 The Impact of Inflammation and Immune Activation on B Cell Differentiation During HIV-1 Infection Frontiers in Immunology. 2011 | Pubmed ID: 22566879 IL-7 Promotes CD95-induced Apoptosis in B Cells Via the IFN-γ/STAT1 Pathway PloS One. 2011 | Pubmed ID: 22194871 Survival and Proliferation of CD28- T Cells During HIV-1 Infection Relate to the Amplitude of Viral Replication The Journal of Infectious Diseases. Jun, 2011 | Pubmed ID: 21592996 Measles Outbreak in Africa--is There a Link to the HIV-1 Epidemic? PLoS Pathogens. Feb, 2011 | Pubmed ID: 21347342 New Therapy to Revert Dysfunctional Antibody Responses During HIV-1 Infection The Journal of Clinical Investigation. Nov, 2010 | Pubmed ID: 20972328 Systemic FasL and TRAIL Neutralisation Reduce Leishmaniasis Induced Skin Ulceration PLoS Neglected Tropical Diseases. 2010 | Pubmed ID: 20967287 Dysfunctional B-cell Responses During HIV-1 Infection: Implication for Influenza Vaccination and Highly Active Antiretroviral Therapy The Lancet. Infectious Diseases. Jul, 2010 | Pubmed ID: 20610332 Timing of HAART Defines the Integrity of Memory B Cells and the Longevity of Humoral Responses in HIV-1 Vertically-infected Children Proceedings of the National Academy of Sciences of the United States of America. May, 2009 | Pubmed ID: 19416836 CD27(-) B-cells Produce Class Switched and Somatically Hyper-mutated Antibodies During Chronic HIV-1 Infection PloS One. 2009 | Pubmed ID: 19412542 Altered Expression of the Receptor-ligand Pair CXCR5/CXCL13 in B Cells During Chronic HIV-1 Infection Blood. Dec, 2008 | Pubmed ID: 18780835 Immunity Against HIV/AIDS, Malaria, and Tuberculosis During Co-infections with Neglected Infectious Diseases: Recommendations for the European Union Research Priorities PLoS Neglected Tropical Diseases. Jun, 2008 | Pubmed ID: 18575596 Priming of T Cells to Fas-mediated Proliferative Signals by Interleukin-7 Blood. Aug, 2008 | Pubmed ID: 18441236 B Cell Immunopathology During HIV-1 Infection: Lessons to Learn for HIV-1 Vaccine Design Vaccine. Jun, 2008 | Pubmed ID: 18164520 Chemokine CXCL12 Enhances Proliferation in Pre-B-ALL Via STAT5 Activation Pediatric Blood & Cancer. Apr, 2008 | Pubmed ID: 17914737 Altered Distribution of Natural Killer Cell Subsets Identified by CD56, CD27 and CD70 in Primary and Chronic Human Immunodeficiency Virus-1 Infection Immunology. Feb, 2008 | Pubmed ID: 17627773 Relationship Between Serum IL-7 Concentrations and Lymphopenia Upon Different Levels of HIV Immune Control AIDS (London, England). May, 2007 | Pubmed ID: 17457102 Potential Role for IL-7 in Fas-mediated T Cell Apoptosis During HIV Infection Journal of Immunology (Baltimore, Md. : 1950). Apr, 2007 | Pubmed ID: 17404319 FasL and TRAIL Induce Epidermal Apoptosis and Skin Ulceration Upon Exposure to Leishmania Major The American Journal of Pathology. Jan, 2007 | Pubmed ID: 17200196 Loss of Memory B Cells Impairs Maintenance of Long-term Serologic Memory During HIV-1 Infection Blood. Sep, 2006 | Pubmed ID: 16645169 Loss of IL-7Ralpha is Associated with CD4 T-cell Depletion, High Interleukin-7 Levels and CD28 Down-regulation in HIV Infected Patients AIDS (London, England). Dec, 2005 | Pubmed ID: 16284456 Primary HIV-1 Infection Sets the Stage for Important B Lymphocyte Dysfunctions AIDS (London, England). Nov, 2005 | Pubmed ID: 16260900 The Contribution of the Fas/FasL Apoptotic Pathway in Ulcer Formation During Leishmania Major-induced Cutaneous Leishmaniasis The American Journal of Pathology. Apr, 2005 | Pubmed ID: 15793290 Effects of Potent Antiretroviral Therapy on the Immune Activation Marker Soluble CD27 in Patients Infected with HIV-1 Subtypes A-D Journal of Medical Virology. Mar, 2004 | Pubmed ID: 14748056 Soluble Factors Released by Virus Specific Activated Cytotoxic T-lymphocytes Induce Apoptotic Death of Astroglioma Cell Lines Brain Pathology (Zurich, Switzerland). Apr, 2003 | Pubmed ID: 12744470 Author Spotlight: Advancing Antiviral Strategies through Novel Immunocapture and Mass Spectrometry Techniques Maryam Sahi1, Sarah Andersson1, Cecilia Mattson1, Matilda Dale1, Sofia Kagiolglou1, Camilla Hofström2, Helena Persson2, Jonas Klingström3,4, Francesca Chiodi5, Claudia Fredolini1 1Affinity Proteomics-Stockholm Unit, SciLifeLab, Division of Affinity Proteomics, Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), KTH Royal Institute of Technology, 2Human Antibody Therapeutics Unit, SciLifeLab, Division of Drug Discovery and Development, Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), KTH Royal Institute of Technology, 3Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 4Public Health Agency of Sweden, 5Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet JoVE 66230 Imunologia e Infecção
Author Spotlight: Advancing Antiviral Strategies through Novel Immunocapture and Mass Spectrometry Techniques Maryam Sahi1, Sarah Andersson1, Cecilia Mattson1, Matilda Dale1, Sofia Kagiolglou1, Camilla Hofström2, Helena Persson2, Jonas Klingström3,4, Francesca Chiodi5, Claudia Fredolini1 1Affinity Proteomics-Stockholm Unit, SciLifeLab, Division of Affinity Proteomics, Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), KTH Royal Institute of Technology, 2Human Antibody Therapeutics Unit, SciLifeLab, Division of Drug Discovery and Development, Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), KTH Royal Institute of Technology, 3Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 4Public Health Agency of Sweden, 5Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet JoVE 66230 Imunologia e Infecção