Jürgen Klempnauer Regenerative Medicine and Experimental Surgery, Department of General, Visceral and Transplant Surgery Hannover Medical School Biography Publications Institution JoVE Articles Jürgen Klempnauer has not added a biography. If you are Jürgen Klempnauer and would like to personalize this page please email our Author Liaison for assistance. Publications Brain Function and Metabolism in Patients with Long-term Tacrolimus Therapy After Kidney Transplantation in Comparison to Patients After Liver Transplantation PloS One. 2020 | Pubmed ID: 32155172 Extended Hepatic Metastasectomy for Renal Cell Carcinoma-new Aspects in Times of Targeted Therapy: a Single-center Experience over Three Decades Langenbeck's Archives of Surgery. Feb, 2020 | Pubmed ID: 31938833 Impact of Immunosuppressive Therapy on Brain Derived Cytokines After Liver Transplantation Transplant Immunology. Feb, 2020 | Pubmed ID: 31669260 Long-term, Prolonged-release Tacrolimus-based Immunosuppression in De Novo Kidney Transplant Recipients: 5-year Prospective Follow-up of the ADHERE Study Patients Transplant International : Official Journal of the European Society for Organ Transplantation. Feb, 2020 | Pubmed ID: 31536654 Abdominal Surgery in Patients with Ventricular Assist Devices: a Single-Center Report ASAIO Journal (American Society for Artificial Internal Organs : 1992). Oct, 2019 | Pubmed ID: 31651459 Quantitative Magnetic Resonance Imaging Indicates Brain Tissue Alterations in Patients After Liver Transplantation PloS One. 2019 | Pubmed ID: 31553760 Cerebral Metabolite Alterations in Patients with Posttransplant Encephalopathy After Liver Transplantation PloS One. 2019 | Pubmed ID: 31442276 Hepatic Encephalopathy Is Reversible in the Long Term After Liver Transplantation Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Nov, 2019 | Pubmed ID: 31437344 Recipient Natural Killer Cells Alter the Course of Rejection of Allogeneic Heart Grafts in Rats PloS One. 2019 | Pubmed ID: 31437165 Improved Survival in Liver Transplant Patients Receiving Prolonged-release Tacrolimus-based Immunosuppression in the European Liver Transplant Registry (ELTR): An Extension Study Transplantation. Sep, 2019 | Pubmed ID: 31343568 Prediction of Survival After Left-sided Pancreatic Resection for Adenocarcinoma: Introduction of a New Prognostic Score Hepatobiliary & Pancreatic Diseases International : HBPD INT. Dec, 2019 | Pubmed ID: 31279680 The Effect of Donor Age and Recipient Characteristics on Renal Outcomes in Patients Receiving Prolonged-Release Tacrolimus After Liver Transplantation: Post-Hoc Analyses of the DIAMOND Study Annals of Transplantation. Jun, 2019 | Pubmed ID: 31160549 Ventilation After Pancreaticoduodenectomy Increases Perioperative Mortality: Identification of Risk Factors and Their Relevance in Germany That Do Not Apply in England Hepatobiliary & Pancreatic Diseases International : HBPD INT. Aug, 2019 | Pubmed ID: 31122750 Prediction of Three-Year Mortality After Deceased Donor Kidney Transplantation in Adults with Pre-Transplant Donor and Recipient Variables Annals of Transplantation. May, 2019 | Pubmed ID: 31097680 Brain Metabolic Alterations in Patients with Long-term Calcineurin Inhibitor Therapy After Liver Transplantation Alimentary Pharmacology & Therapeutics. 06, 2019 | Pubmed ID: 31006881 Transient Increase of Activated Regulatory T Cells Early After Kidney Transplantation Scientific Reports. 01, 2019 | Pubmed ID: 30705299 Investigation of the Influence of Xenoreactive Antibodies on Activation of Complement and Coagulation in an Ex Vivo Perfusion Animal Study Using Porcine Kidneys Transplant International : Official Journal of the European Society for Organ Transplantation. May, 2019 | Pubmed ID: 30597634 Treatment of Cyclosporine Induced Hypertension: Results from a Long-term Observational Study Using Different Antihypertensive Medications Vascular Pharmacology. 04, 2019 | Pubmed ID: 29933079 A Case of Recurrent Pneumoperitoneum and Pneumatosis Intestinalis After Bilateral Lung Transplant Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation. 02, 2019 | Pubmed ID: 28585913 Proposal of Two Prognostic Models for the Prediction of 10-Year Survival After Liver Resection for Colorectal Metastases HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery. 2018 | Pubmed ID: 30420795 Development and Validation of a Prognostic Model for Kidney Function 1 year After Combined Pancreas and Kidney Transplantation Using Pre-transplant Donor and Recipient Variables Langenbeck's Archives of Surgery. Nov, 2018 | Pubmed ID: 30338375 Hangzhou Criteria Are More Accurate Than Milan Criteria in Predicting Long-term Survival After Liver Transplantation for HCC in Germany Langenbeck's Archives of Surgery. Aug, 2018 | Pubmed ID: 30120543 Relevant Prognostic Factors Influencing Outcome of Patients After Surgical Resection of Distal Cholangiocarcinoma BMC Surgery. Aug, 2018 | Pubmed ID: 30103720 Predictive Factors for Survival in Children Receiving Liver Transplants for Wilson's Disease: A Cohort Study Using European Liver Transplant Registry Data Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 09, 2018 | Pubmed ID: 30021057 Renal Cell Cancer After Kidney Transplantation Langenbeck's Archives of Surgery. Aug, 2018 | Pubmed ID: 30003323 Evolutionary Distance Predicts Recurrence After Liver Transplantation in Multifocal Hepatocellular Carcinoma Transplantation. 10, 2018 | Pubmed ID: 29994984 Prognostic Factors for Long-term Survival After Adult Liver Transplantation Langenbeck's Archives of Surgery. Jun, 2018 | Pubmed ID: 29610975 Timing of Parathyroidectomy in Kidney Transplant Candidates with Secondary Hyperparathryroidism: Effect of Pretransplant Versus Early or Late Post-transplant Parathyroidectomy Surgery. 02, 2018 | Pubmed ID: 29284591 Survival of Children After Liver Transplantation for Hepatocellular Carcinoma Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 02, 2018 | Pubmed ID: 29222922 Longterm Calcineurin Inhibitor Therapy and Brain Function in Patients After Liver Transplantation Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 01, 2018 | Pubmed ID: 29156491 Early Tracheostomy Reduces Time of Mechanical Ventilation in Respiratory High-Risk Patients After Liver Transplant Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation. 10, 2018 | Pubmed ID: 29025380 Statistical Approach to Quality Assessment in Liver Transplantation Langenbeck's Archives of Surgery. Feb, 2018 | Pubmed ID: 28889185 Introduction of the Resection Severity Index As Independent Risk Factor Limiting Survival After Resection of Colorectal Liver Metastases Surgical Oncology. Dec, 2017 | Pubmed ID: 29113656 Risk-factors for Nodular Hyperplasia of Parathyroid Glands in SHPT Patients PloS One. 2017 | Pubmed ID: 29040300 Identification of the Resection Severity Index As a Significant Independent Prognostic Factor for Early Mortality and Observed Survival >5 and >10 Years After Liver Resection for Hepatocellular Carcinoma Surgical Oncology. Jun, 2017 | Pubmed ID: 28577724 Identifying Independent Risk Factors for Graft Loss After Primary Liver Transplantation Langenbeck's Archives of Surgery. Aug, 2017 | Pubmed ID: 28573420 Hepatic Encephalopathy Before and Neurological Complications After Liver Transplantation Have No Impact on the Employment Status 1 Year After Transplantation World Journal of Hepatology. Apr, 2017 | Pubmed ID: 28443157 Primary Non-function is Frequently Associated with Fatty Liver Allografts and High Mortality After Re-transplantation Liver International : Official Journal of the International Association for the Study of the Liver. 08, 2017 | Pubmed ID: 28267886 Biliary Complications Following Liver Transplantation: Single-center Experience over Three Decades and Recent Risk Factors World Journal of Hepatology. Jan, 2017 | Pubmed ID: 28217251 Risk Balancing of Cold Ischemic Time Against Night Shift Surgery Possibly Reduces Rates of Reoperation and Perioperative Graft Loss Journal of Transplantation. 2017 | Pubmed ID: 28203455 The Glasgow Prognostic Score and Its Variants Predict Mortality in Living Donor but Not in Deceased Donor Liver Transplantation for Hepatocellular Carcinoma: A Double-center Validation Study Hepatology Research : the Official Journal of the Japan Society of Hepatology. Jul, 2017 | Pubmed ID: 27598002 Liver Transplantation for Hepatic Trauma: A Study From the European Liver Transplant Registry Transplantation. 11, 2016 | Pubmed ID: 27780185 Inhibition of B-cell Activation and Antibody Production by Triggering Inhibitory Signals Via the PD-1/PD-ligand Pathway Xenotransplantation. 09, 2016 | Pubmed ID: 27613101 Identification of Patients at Risk for Renal Impairment After Living Donor Kidney Transplantation Langenbeck's Archives of Surgery. Dec, 2016 | Pubmed ID: 27502290 Independent Pre-Transplant Recipient Cancer Risk Factors After Kidney Transplantation and the Utility of G-Chart Analysis for Clinical Process Control PloS One. 2016 | Pubmed ID: 27398803 Liver Transplantation for Hepatocellular Carcinoma: A Single Center Resume Overlooking Four Decades of Experience Journal of Transplantation. 2016 | Pubmed ID: 27057348 The New Liver Allocation Score for Transplantation is Validated and Improved Transplant Survival Benefit in Germany but Not in the United Kingdom Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 06, 2016 | Pubmed ID: 26947766 Liver Transplantation for Adenomatosis: European Experience Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Apr, 2016 | Pubmed ID: 26919265 Post-Operative Hemorrhage After Liver Transplantation: Risk Factors and Long-Term Outcome Annals of Transplantation. Jan, 2016 | Pubmed ID: 26818716 Prediction of Survival and Tumor Recurrence in Patients Undergoing Surgery for Pancreatic Neuroendocrine Neoplasms Journal of Surgical Oncology. Feb, 2016 | Pubmed ID: 26709239 Liver Resection for Non-Colorectal Liver Metastases - Standards and Extended Indications Viszeralmedizin. Dec, 2015 | Pubmed ID: 26889142 The C.503T>C Polymorphism in the Human KLRB1 Gene Alters Ligand Binding and Inhibitory Potential of CD161 Molecules PloS One. 2015 | Pubmed ID: 26309225 Model of End-Stage Liver Disease Score and Derived Variants Lack Prognostic Ability After Liver Transplantation Annals of Transplantation. Aug, 2015 | Pubmed ID: 26242315 Evaluation of the Biological Tolerability of the Starch-based Medical Device 4DryField® PH in Vitro and in Vivo a Rat Model Journal of Biomaterials Applications. Oct, 2015 | Pubmed ID: 26116021 Long-term Outcome of Liver Transplant Patients with Budd-Chiari Syndrome Secondary to Myeloproliferative Neoplasms Liver International : Official Journal of the International Association for the Study of the Liver. Aug, 2015 | Pubmed ID: 25736096 Risk Factors for Short- and Long-term Mortality in Liver Transplant Recipients with MELD Score ≥30 Annals of Transplantation. Jan, 2015 | Pubmed ID: 25630462 A Pocket Guide to Identify Patients at Risk for Chronic Kidney Disease After Liver Transplantation Transplant International : Official Journal of the European Society for Organ Transplantation. May, 2015 | Pubmed ID: 25581324 Comparable Outcome of Liver Transplantation with Histidine-tryptophan-ketoglutarate Vs. University of Wisconsin Preservation Solution: a Retrospective Observational Double-center Trial BMC Gastroenterology. Sep, 2014 | Pubmed ID: 25263587 Species-specific Regulation of Fibrinogen Synthesis with Implications for Porcine Hepatocyte Xenotransplantation Xenotransplantation. Sep-Oct, 2014 | Pubmed ID: 25175927 Pig to Rat Cell Transplantation: Reduced Cellular and Antibody Responses to Xenografts Overexpressing PD-L1 Xenotransplantation. Nov-Dec, 2014 | Pubmed ID: 25041075 Explanted Diseased Livers - a Possible Source of Metabolic Competent Primary Human Hepatocytes PloS One. 2014 | Pubmed ID: 24999631 Helicobacter Hepaticus Induces an Inflammatory Response in Primary Human Hepatocytes PloS One. 2014 | Pubmed ID: 24932686 Inhibition of Autophagic Flux by Salinomycin Results in Anti-cancer Effect in Hepatocellular Carcinoma Cells PloS One. 2014 | Pubmed ID: 24816744 Recombinant Human Antithrombin Prevents Xenogenic Activation of Hemostasis in a Model of Pig-to-human Kidney Transplantation Xenotransplantation. Jul-Aug, 2014 | Pubmed ID: 24807299 Nitrosative Stress Does Not Change During Orthotopic Liver Transplantation Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Jun, 2014 | Pubmed ID: 24616179 Long-term Results After Adult Ex Situ Split Liver Transplantation Since Its Introduction in 1987 World Journal of Surgery. Jul, 2014 | Pubmed ID: 24414197 Islet Infiltration, Cytokine Expression and Beta Cell Death in the NOD Mouse, BB Rat, Komeda Rat, LEW.1AR1-iddm Rat and Humans with Type 1 Diabetes Diabetologia. Mar, 2014 | Pubmed ID: 24310561 Insulin Dependence and Pancreatic Enzyme Replacement Therapy Are Independent Prognostic Factors for Long-term Survival After Operation for Chronic Pancreatitis Surgery. Feb, 2014 | Pubmed ID: 24287147 Long-term Outcome Analysis of Liver Transplantation for Severe Hepatic Trauma The Journal of Trauma and Acute Care Surgery. Nov, 2013 | Pubmed ID: 24158208 Incidence and Long-term Risk of De Novo Malignancies After Liver Transplantation with Implications for Prevention and Detection Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Nov, 2013 | Pubmed ID: 24106037 Long-term Results After Treatment of Very Low-, Low-, and High-risk Thyroid Cancers in a Combined Setting of Thyroidectomy and Radio Ablation Therapy in Euthyroidism International Journal of Endocrinology. 2013 | Pubmed ID: 23935620 Extended Pancreas Donor Program - the EXPAND Study Rationale and Study Protocol Transplantation Research. Jul, 2013 | Pubmed ID: 23816330 High-urgency Renal Transplantation: Indications and Long-term Outcomes Journal of Transplantation. 2013 | Pubmed ID: 23476738 Impact of Salinomycin on Human Cholangiocarcinoma: Induction of Apoptosis and Impairment of Tumor Cell Proliferation in Vitro BMC Cancer. Oct, 2012 | Pubmed ID: 23057720 The Donor-Risk-Index, ECD-Score and D-MELD-Score All Fail to Predict Short-term Outcome After Liver Transplantation with Acceptable Sensitivity and Specificity Annals of Transplantation : Quarterly of the Polish Transplantation Society. Jul-Sep, 2012 | Pubmed ID: 23018250 High Rate of Unperceived Hearing Loss in Patients After Liver Transplantation Clinical Transplantation. Jul-Aug, 2012 | Pubmed ID: 22280451 Observations with Impact on the Indication for Kinetic Therapy in Critically Ill Liver Transplant Patients Annals of Transplantation. Oct-Dec, 2011 | Pubmed ID: 22210418 Boerhaave-Syndrom Als Komplikation Der Koloskopie-Vorbereitung: Ein Fallbericht Journal of Medical Case Reports. 2011 | Pubmed ID: 22054124 Serum Ferritin Concentration and Transferrin Saturation Before Liver Transplantation Predict Decreased Long-term Recipient Survival Hepatology (Baltimore, Md.). Dec, 2011 | Pubmed ID: 21898488 Multizentrisch Bewertung Des Modells Für Endstadium Leber Krankheit-basierten Zuweisung Und Überleben Nach Lebertransplantation in Deutschland--Einschränkungen Der Kränksten 'ersten'-Konzept Transplant International : Official Journal of the European Society for Organ Transplantation. Jan, 2011 | Pubmed ID: 20819196 Measurement and Diagnostic Use of Hepatic Cytochrome P450 Metabolism of Oleic Acid in Liver Disease Liver International : Official Journal of the International Association for the Study of the Liver. Sep, 2010 | Pubmed ID: 20629947 The Introduction of MELD-based Organ Allocation Impacts 3-month Survival After Liver Transplantation by Influencing Pretransplant Patient Characteristics Transplant International : Official Journal of the European Society for Organ Transplantation. Oct, 2009 | Pubmed ID: 19619170 The L-arginine/NO Pathway in End-stage Liver Disease and During Orthotopic Liver and Kidney Transplantation: Biological and Analytical Ramifications Nitric Oxide : Biology and Chemistry. Feb, 2009 | Pubmed ID: 18948222 Gender-incompatible Liver Transplantation is Not a Risk Factor for Patient Survival Liver International : Official Journal of the International Association for the Study of the Liver. Feb, 2009 | Pubmed ID: 18673439 Prediction of Survival After Liver Transplantation by Pre-transplant Parameters Scandinavian Journal of Gastroenterology. 2008 | Pubmed ID: 18569992 Indications for and Outcomes After Combined Lung and Liver Transplantation: a Single-center Experience on 13 Consecutive Cases Transplantation. Feb, 2008 | Pubmed ID: 18347530 Prognostic Implications of Lactate, Bilirubin, and Etiology in German Patients with Acute Liver Failure Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Mar, 2008 | Pubmed ID: 18328438 Induction of Heme Oxygenase-1 Improves the Survival of Pancreas Grafts by Prevention of Pancreatitis After Transplantation Transplantation. Dec, 2007 | Pubmed ID: 18165777 FTY720 Verbessert Überleben Nach Vorübergehender Ischämie Und Reperfusion Der Hinteren Gliedmaßen The Journal of Trauma. Aug, 2007 | Pubmed ID: 17693822 Paediatric Kidney Transplantation in Small Children-- a Single Centre Experience Transplant International : Official Journal of the European Society for Organ Transplantation. Mar, 2006 | Pubmed ID: 16441768 Conformational Restraints and Flexibility of 14-meric Peptides in Complex with HLA-B*3501 Journal of Immunology (Baltimore, Md. : 1950). Nov, 2004 | Pubmed ID: 15494511 Auswirkungen Der Spender-Empfänger-MHC-Matching Auf Experimentelle Inselchen Allotransplantat Überleben in Naiven Und Vorsensibilisierten Lewis-Ratten Transplantation. Jul, 2004 | Pubmed ID: 15257057 IGF-1R, IGF-1 and IGF-2 Expression As Potential Prognostic and Predictive Markers in Colorectal-cancer Virchows Archiv : an International Journal of Pathology. Aug, 2003 | Pubmed ID: 12845531 Prognostic Significance of Calcium-binding Protein S100A4 in Colorectal Cancer Gastroenterology. Nov, 2002 | Pubmed ID: 12404222 Review: Surgical Shunts and Encephalopathy Metabolic Brain Disease. Jun, 2001 | Pubmed ID: 11726084 Carcinoma of the Ampulla of Vater: Determinants of Long-term Survival in 94 Resected Patients HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery. 1998 | Pubmed ID: 9830575 Ein immunologisches Modell für heterotopische Herz- und Herzmuskelzelltransplantation bei Ratten Clara A. Weigle1, Thorsten Lieke1, Florian W. R. Vondran1, Kai Timrott1, Jürgen Klempnauer1, Oliver Beetz1 1Regenerative Medicine and Experimental Surgery, Department of General, Visceral and Transplant Surgery, Hannover Medical School JoVE 60956 Imunologia e Infecção
Ein immunologisches Modell für heterotopische Herz- und Herzmuskelzelltransplantation bei Ratten Clara A. Weigle1, Thorsten Lieke1, Florian W. R. Vondran1, Kai Timrott1, Jürgen Klempnauer1, Oliver Beetz1 1Regenerative Medicine and Experimental Surgery, Department of General, Visceral and Transplant Surgery, Hannover Medical School JoVE 60956 Imunologia e Infecção