Peter Bronsert Institute for Surgical Pathology, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Biography Publications Institution JoVE Articles Peter Bronsert has not added a biography. If you are Peter Bronsert and would like to personalize this page please email our Author Liaison for assistance. Publications Influence of Urethra Sparing on Tumor Control Probability and Normal Tissue Complication Probability in Focal Dose Escalated Hypofractionated Radiotherapy: A Planning Study Based on Histopathology Reference Frontiers in Oncology. 2021 | Pubmed ID: 34055621 Alteration of Tissue Marking Dyes Depends on Used Chromogen During Immunohistochemistry Cells. Apr, 2021 | Pubmed ID: 33917667 Surgeon Vs Pathologist for Prediction of Pancreatic Fistula: Results from the Randomized Multicenter RECOPANC Study Journal of the American College of Surgeons. Jun, 2021 | Pubmed ID: 33887486 The Impact of the Co-registration Technique and Analysis Methodology in Comparison Studies Between Advanced Imaging Modalities and Whole-mount-histology Reference in Primary Prostate Cancer Scientific Reports. Mar, 2021 | Pubmed ID: 33712662 Human Primary Breast Cancer Stem Cells Are Characterized by Epithelial-Mesenchymal Plasticity International Journal of Molecular Sciences. Feb, 2021 | Pubmed ID: 33670400 Uncovering the Invisible-prevalence, Characteristics, and Radiomics Feature-based Detection of Visually Undetectable Intraprostatic Tumor Lesions in GaPSMA-11 PET Images of Patients with Primary Prostate Cancer European Journal of Nuclear Medicine and Molecular Imaging. 06, 2021 | Pubmed ID: 33210239 Intraprostatic Tumor Segmentation on PSMA PET Images in Patients with Primary Prostate Cancer with a Convolutional Neural Network Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jun, 2021 | Pubmed ID: 33127624 Immunohistological Composition of Peri-implantitis Affected Tissue Around Ceramic Implants-A Pilot Study Journal of Periodontology. 04, 2021 | Pubmed ID: 32839977 FAK Inhibition Radiosensitizes Pancreatic Ductal Adenocarcinoma Cells in Vitro Strahlentherapie Und Onkologie : Organ Der Deutschen Rontgengesellschaft ... [et Al]. Jan, 2021 | Pubmed ID: 32705304 Comparison of Manual and Semi-Automatic [F]PSMA-1007 PET Based Contouring Techniques for Intraprostatic Tumor Delineation in Patients With Primary Prostate Cancer and Validation With Histopathology As Standard of Reference Frontiers in Oncology. 2020 | Pubmed ID: 33365271 Prognostic Impact of Tumor Budding and EMT in Periampullary Adenocarcinoma: a Quantitative Approach Journal of Cancer. 2020 | Pubmed ID: 33046968 Neoplastic-Stromal Cell Cross-talk Regulates Matrisome Expression in Pancreatic Cancer Molecular Cancer Research : MCR. 12, 2020 | Pubmed ID: 32873625 High Numbers and Densities of PD1 T-Follicular Helper Cells in Triple-Negative Breast Cancer Draining Lymph Nodes Are Associated with Lower Survival International Journal of Molecular Sciences. Aug, 2020 | Pubmed ID: 32824917 Pattern of Recurrence and Patient Survival After Perioperative Chemotherapy with 5-FU, Leucovorin, Oxaliplatin and Docetaxel (FLOT) for Locally Advanced Esophagogastric Adenocarcinoma in Patients Treated Outside Clinical Trials Journal of Clinical Medicine. Aug, 2020 | Pubmed ID: 32824326 Author Correction: Evaluation of Molecular Subtypes and Clonal Selection During Establishment of Patient-derived Tumor Xenografts from Gastric Adenocarcinoma Communications Biology. Jul, 2020 | Pubmed ID: 32709976 Conditional Gene Targeting Reveals Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression Cancers. Jul, 2020 | Pubmed ID: 32707827 Alignment of Stroma Fibers, Microvessel Density and Immune Cell Populations Determine Overall Survival in Pancreatic Cancer-An Analysis of Stromal Morphology PloS One. 2020 | Pubmed ID: 32658932 Deep Multiple Instance Learning Classifies Subtissue Locations in Mass Spectrometry Images from Tissue-level Annotations Bioinformatics (Oxford, England). 07, 2020 | Pubmed ID: 32657378 Evaluation of Molecular Subtypes and Clonal Selection During Establishment of Patient-derived Tumor Xenografts from Gastric Adenocarcinoma Communications Biology. 07, 2020 | Pubmed ID: 32647357 Author Correction: Intraoperative Detection of Circulating Tumor Cells in Pulmonary Venous Blood During Metastasectomy for Colorectal Lung Metastases Scientific Reports. May, 2020 | Pubmed ID: 32358537 Systematic Analysis of Accuracy in Predicting Complete Oncological Resection in Pancreatic Cancer Patients-Proposal of a New Simplified Borderline Resectability Definition Cancers. Apr, 2020 | Pubmed ID: 32260453 Distinct Bone Marrow Morphologic Features Discriminate Myelodysplastic Syndromes Patients with and Without an Early Platelet Response to Decitabine British Journal of Haematology. 06, 2020 | Pubmed ID: 32207144 γδ T-cell Receptors Derived from Breast Cancer-Infiltrating T Lymphocytes Mediate Antitumor Reactivity Cancer Immunology Research. 04, 2020 | Pubmed ID: 32019779 A Four-Chemokine Signature Is Associated with a T-cell-Inflamed Phenotype in Primary and Metastatic Pancreatic Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2020 | Pubmed ID: 31964786 Tumor Budding As a Prognostic Factor in Pancreatic Ductal Adenocarcinoma Virchows Archiv : an International Journal of Pathology. Apr, 2020 | Pubmed ID: 31786688 A Lab-on-a-chip for Rapid MiRNA Extraction PloS One. 2019 | Pubmed ID: 31856234 Accessible and Reproducible Mass Spectrometry Imaging Data Analysis in Galaxy GigaScience. 12, 2019 | Pubmed ID: 31816088 Validation of Different PSMA-PET/CT-based Contouring Techniques for Intraprostatic Tumor Definition Using Histopathology As Standard of Reference Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. 12, 2019 | Pubmed ID: 31431386 [Ga-]PSMA-11 PET/CT and Multiparametric MRI for Gross Tumor Volume Delineation in a Slice by Slice Analysis with Whole Mount Histopathology As a Reference Standard - Implications for Focal Radiotherapy Planning in Primary Prostate Cancer Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. 12, 2019 | Pubmed ID: 31431366 Radiomic Features from PSMA PET for Non-invasive Intraprostatic Tumor Discrimination and Characterization in Patients with Intermediate- and High-risk Prostate Cancer - a Comparison Study with Histology Reference Theranostics. 2019 | Pubmed ID: 31131055 Addition of IMP3 to L1CAM for Discrimination Between Low- and High-grade Endometrial Carcinomas: a European Network for Individualised Treatment of Endometrial Cancer Collaboration Study Human Pathology. 07, 2019 | Pubmed ID: 31054899 Prognostic Relevance of Preoperative Bilirubin-adjusted Serum Carbohydrate Antigen 19-9 in a Multicenter Subset Analysis of 179 Patients with Distal Cholangiocarcinoma HPB : the Official Journal of the International Hepato Pancreato Biliary Association. 11, 2019 | Pubmed ID: 30956162 Non-Metastatic Esophageal Adenocarcinoma: Circulating Tumor Cells in the Course of Multimodal Tumor Treatment Cancers. Mar, 2019 | Pubmed ID: 30901891 Genotyping of Circulating Cell-free DNA Enables Noninvasive Tumor Detection in Myxoid Liposarcomas International Journal of Cancer. 08, 2019 | Pubmed ID: 30779112 ADAM9 Contributes to Vascular Invasion in Pancreatic Ductal Adenocarcinoma Molecular Oncology. 02, 2019 | Pubmed ID: 30556643 Inhibition of MTORC2/RICTOR Impairs Melanoma Hepatic Metastasis Neoplasia (New York, N.Y.). 12, 2018 | Pubmed ID: 30404068 [Three-dimensional Reconstruction of Solid Tumors : Morphological Evidence for Tumor Heterogeneity] Der Pathologe. Dec, 2018 | Pubmed ID: 30361775 Does the Site of Primary Colorectal Cancer Influence the Outcome After Resection of Isolated Liver Metastases? Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 10, 2018 | Pubmed ID: 30055964 Intraoperative Detection of Circulating Tumor Cells in Pulmonary Venous Blood During Metastasectomy for Colorectal Lung Metastases Scientific Reports. 06, 2018 | Pubmed ID: 29884810 Focal Dose Escalation for Prostate Cancer Using Ga-HBED-CC PSMA PET/CT and MRI: a Planning Study Based on Histology Reference Radiation Oncology (London, England). May, 2018 | Pubmed ID: 29716617 Identification and Validation of a Diagnostic and Prognostic Multi-Gene Biomarker Panel for Pancreatic Ductal Adenocarcinoma Frontiers in Genetics. 2018 | Pubmed ID: 29675033 Morphology of Immunomodulation in Breast Cancer Tumor Draining Lymph Nodes Depends on Stage and Intrinsic Subtype Scientific Reports. 03, 2018 | Pubmed ID: 29593307 Reproducible Proteomics Sample Preparation for Single FFPE Tissue Slices Using Acid-labile Surfactant and Direct Trypsinization Clinical Proteomics. 2018 | Pubmed ID: 29527141 Viability and Biocompatibility of an Adhesive System for Intrarenal Embedding and Endoscopic Removal of Small Residual Fragments in Minimally-invasive Stone Treatment in an in Vivo Pig Model World Journal of Urology. Apr, 2018 | Pubmed ID: 29368229 Prognostic Influence of Hepatic Margin After Resection of Colorectal Liver Metastasis: Role of Modern Preoperative Chemotherapy International Journal of Colorectal Disease. Jan, 2018 | Pubmed ID: 29098384 A Deep Conical Agarose Microwell Array for Adhesion Independent Three-dimensional Cell Culture and Dynamic Volume Measurement Lab on a Chip. 12, 2017 | Pubmed ID: 29211089 A Molecular Intravascular Ultrasound Contrast Agent Allows Detection of Activated Platelets on the Surface of Symptomatic Human Plaques Atherosclerosis. Dec, 2017 | Pubmed ID: 29101838 Author Correction: Pancreatic Cancer: Circulating Tumor Cells and Primary Tumors Show Heterogeneous KRAS Mutations Scientific Reports. 10, 2017 | Pubmed ID: 29079791 KDM4 Inhibition Targets Breast Cancer Stem-like Cells Cancer Research. 11, 2017 | Pubmed ID: 28883001 Pancreatic Cancer: Circulating Tumor Cells and Primary Tumors Show Heterogeneous KRAS Mutations Scientific Reports. 07, 2017 | Pubmed ID: 28674438 The Role of Fibroblasts in Pancreatic Cancer: Extracellular Matrix Versus Paracrine Factors Translational Oncology. Aug, 2017 | Pubmed ID: 28658650 Survival Outcome and Prognostic Factors After Pancreatoduodenectomy for Distal Bile Duct Carcinoma: a Retrospective Multicenter Study Langenbeck's Archives of Surgery. Jun, 2017 | Pubmed ID: 28612115 Form Follows Function: Morphological and Immunohistological Insights into Epithelial-mesenchymal Transition Characteristics of Tumor Buds Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. May, 2017 | Pubmed ID: 28475002 The EMT-activator Zeb1 is a Key Factor for Cell Plasticity and Promotes Metastasis in Pancreatic Cancer Nature Cell Biology. 05, 2017 | Pubmed ID: 28414315 The Prognostic Impact of the Carcinoembryonic Antigen in Ampullary Cancer - A Retrospective Single Center Study Journal of Cancer. 2017 | Pubmed ID: 28367245 A Novel ZEB1/HAS2 Positive Feedback Loop Promotes EMT in Breast Cancer Oncotarget. Feb, 2017 | Pubmed ID: 28086235 Pregnancy Specific β-1 Glycoprotein 1 is Expressed in Pancreatic Ductal Adenocarcinoma and Its Subcellular Localization Correlates with Overall Survival Journal of Cancer. 2016 | Pubmed ID: 27877217 TNM-O: Ontology Support for Staging of Malignant Tumours Journal of Biomedical Semantics. 11, 2016 | Pubmed ID: 27842575 Gastrin-releasing Peptide Receptor Imaging in Breast Cancer Using the Receptor Antagonist (68)Ga-RM2 And PET Theranostics. 2016 | Pubmed ID: 27446498 ESOPEC: Prospective Randomized Controlled Multicenter Phase III Trial Comparing Perioperative Chemotherapy (FLOT Protocol) to Neoadjuvant Chemoradiation (CROSS Protocol) in Patients with Adenocarcinoma of the Esophagus (NCT02509286) BMC Cancer. 07, 2016 | Pubmed ID: 27435280 Formalin-Fixed, Paraffin-Embedded Tissues (FFPE) As a Robust Source for the Profiling of Native and Protease-Generated Protein Amino Termini Molecular & Cellular Proteomics : MCP. 06, 2016 | Pubmed ID: 27087653 Characterization of Various Cell Lines from Different Ampullary Cancer Subtypes and Cancer Associated Fibroblast-mediated Responses BMC Cancer. Mar, 2016 | Pubmed ID: 26951071 Mesopancreatic Stromal Clearance Defines Curative Resection of Pancreatic Head Cancer and Can Be Predicted Preoperatively by Radiologic Parameters: A Retrospective Study Medicine. Jan, 2016 | Pubmed ID: 26817896 KRAS Mutations in Pancreatic Circulating Tumor Cells: a Pilot Study Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. Jun, 2016 | Pubmed ID: 26684803 Identification of a Blood-borne MiRNA Signature of Synovial Sarcoma Molecular Cancer. Aug, 2015 | Pubmed ID: 26250552 Quantitative Proteomic Analysis of Formalin-fixed, Paraffin-embedded Clear Cell Renal Cell Carcinoma Tissue Using Stable Isotopic Dimethylation of Primary Amines BMC Genomics. Jul, 2015 | Pubmed ID: 26220445 ZEB1-associated Drug Resistance in Cancer Cells is Reversed by the Class I HDAC Inhibitor Mocetinostat EMBO Molecular Medicine. Jun, 2015 | Pubmed ID: 25872941 Role of Cannabinoid Receptor CB2 in HER2 Pro-oncogenic Signaling in Breast Cancer Journal of the National Cancer Institute. Jun, 2015 | Pubmed ID: 25855725 Perioperative and Long-term Outcome After Standard Pancreaticoduodenectomy, Additional Portal Vein and Multivisceral Resection for Pancreatic Head Cancer Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Mar, 2015 | Pubmed ID: 25567663 Histological Analysis of γδ T Lymphocytes Infiltrating Human Triple-Negative Breast Carcinomas Frontiers in Immunology. 2014 | Pubmed ID: 25540645 Prognostic Significance of Zinc Finger E-box Binding Homeobox 1 (ZEB1) Expression in Cancer Cells and Cancer-associated Fibroblasts in Pancreatic Head Cancer Surgery. Jul, 2014 | Pubmed ID: 24929761 Multimodal Treatment of Locally Advanced Esophageal Adenocarcinoma: Which Regimen Should We Choose? Outcome Analysis of Perioperative Chemotherapy Versus Neoadjuvant Chemoradiation in 105 Patients Journal of Surgical Oncology. Mar, 2014 | Pubmed ID: 24277235 Intestinal-type of Differentiation Predicts Favourable Overall Survival: Confirmatory Clinicopathological Analysis of 198 Periampullary Adenocarcinomas of Pancreatic, Biliary, Ampullary and Duodenal Origin BMC Cancer. Sep, 2013 | Pubmed ID: 24053229 Improved Long-term Survival After Esophagectomy for Esophageal Cancer: Influence of Epidemiologic Shift and Neoadjuvant Therapy Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Jul, 2013 | Pubmed ID: 23636882 Limited Resection for Duodenal Gastrointestinal Stromal Tumors: Surgical Management and Clinical Outcome World Journal of Gastrointestinal Surgery. Feb, 2013 | Pubmed ID: 23515427 Outcome After Repeat Resection of Liver Metastases from Colorectal Cancer International Journal of Colorectal Disease. Aug, 2013 | Pubmed ID: 23468250 Organotypic Slice Cultures as Preclinical Models of Tumor Microenvironment in Primary Pancreatic Cancer and Metastasis Rüdiger Braun1, Olha Lapshyna1, Susanne Eckelmann2,3, Kim Honselmann1, Louisa Bolm1, Meike ten Winkel1, Steffen Deichmann1, Oliver Schilling4, Charli Kruse2,3, Tobias Keck1, Ulrich Wellner1, Peter Bronsert4,5,6, Matthias Brandenburger3 1Department of Surgery, University Medical Center Schleswig-Holstein, 2Institute of Medical and Marine Biotechnology, University of Lübeck, 3Fraunhofer Research and Development Center for Marine and Cellular Biotechnology, 4Institute for Surgical Pathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 5Tumorbank Comprehensive Cancer Center Freiburg, Medical Center - University of Freiburg, 6Core Facility Histopathology and Digital Pathology Freiburg, Medical Center - University of Freiburg JoVE 62541 Medicina
Organotypic Slice Cultures as Preclinical Models of Tumor Microenvironment in Primary Pancreatic Cancer and Metastasis Rüdiger Braun1, Olha Lapshyna1, Susanne Eckelmann2,3, Kim Honselmann1, Louisa Bolm1, Meike ten Winkel1, Steffen Deichmann1, Oliver Schilling4, Charli Kruse2,3, Tobias Keck1, Ulrich Wellner1, Peter Bronsert4,5,6, Matthias Brandenburger3 1Department of Surgery, University Medical Center Schleswig-Holstein, 2Institute of Medical and Marine Biotechnology, University of Lübeck, 3Fraunhofer Research and Development Center for Marine and Cellular Biotechnology, 4Institute for Surgical Pathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 5Tumorbank Comprehensive Cancer Center Freiburg, Medical Center - University of Freiburg, 6Core Facility Histopathology and Digital Pathology Freiburg, Medical Center - University of Freiburg JoVE 62541 Medicina