Xavier Declèves Université Paris Descartes, Faculté de Pharmacie Université Paris Diderot Biography Publications Institution JoVE Articles Xavier Declèves has not added a biography. If you are Xavier Declèves and would like to personalize this page please email our Author Liaison for assistance. Publications Blood-brain and Retinal Barriers Show Dissimilar ABC Transporter Impacts and Concealed Effect of P-glycoprotein on a Novel Verapamil Influx Carrier British Journal of Pharmacology. Oct, 2015 | Pubmed ID: 26507673 Usefulness of Plasma Drug Monitoring in Severe Baclofen Poisoning Clinical Toxicology (Philadelphia, Pa.). Nov, 2015 | Pubmed ID: 26415080 Pharmacophore-based Discovery of Inhibitors of a Novel Drug/proton Antiporter in Human Brain Endothelial HCMEC/D3 Cell Line British Journal of Pharmacology. Oct, 2015 | Pubmed ID: 26220580 A Polyspecific Drug/proton Antiporter Mediates Diphenhydramine and Clonidine Transport at the Mouse Blood-retinal Barrier British Journal of Pharmacology. Oct, 2015 | Pubmed ID: 26177775 Population Pharmacokinetics and Dosing Optimization of Teicoplanin in Children with Malignant Haematological Disease British Journal of Clinical Pharmacology. Nov, 2015 | Pubmed ID: 26138279 Aryl Hydrocarbon Receptor Regulates CYP1B1 but Not ABCB1 and ABCG2 in HCMEC/D3 Human Cerebral Microvascular Endothelial Cells After TCDD Exposure Brain Research. Jul, 2015 | Pubmed ID: 25858487 Methadone Dose in Heroin-dependent Patients: Role of Clinical Factors, Comedications, Genetic Polymorphisms and Enzyme Activity British Journal of Clinical Pharmacology. Jun, 2015 | Pubmed ID: 25556837 Carrier-mediated Cocaine Transport at the Blood-brain Barrier As a Putative Mechanism in Addiction Liability The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). Jan, 2015 | Pubmed ID: 25539501 Hypoxia Interferes with Aryl Hydrocarbon Receptor Pathway in HCMEC/D3 Human Cerebral Microvascular Endothelial Cells Journal of Neurochemistry. Feb, 2015 | Pubmed ID: 25327972 Antidepressant Agents in Short Bowel Syndrome Clinical Therapeutics. Dec, 2014 | Pubmed ID: 25450472 Effect of a Roux-en-Y Gastric Bypass on the Pharmacokinetics of Oral Morphine Using a Population Approach Clinical Pharmacokinetics. Oct, 2014 | Pubmed ID: 25141973 Comparing Translational Population-PBPK Modelling of Brain Microdialysis with Bottom-up Prediction of Brain-to-plasma Distribution in Rat and Human Biopharmaceutics & Drug Disposition. Nov, 2014 | Pubmed ID: 25044007 A Physiologically Based Modeling Strategy During Preclinical CNS Drug Development Molecular Pharmaceutics. Mar, 2014 | Pubmed ID: 24446829 Classification of and Risk Factors for Estrogen Deprivation Pain Syndromes Related to Aromatase Inhibitor Treatments in Women with Breast Cancer: a Prospective Multicenter Cohort Study The Journal of Pain : Official Journal of the American Pain Society. Mar, 2014 | Pubmed ID: 24365325 Human ABC Transporters at Blood-CNS Interfaces As Determinants of CNS Drug Penetration Current Pharmaceutical Design. 2014 | Pubmed ID: 23789951 Synthetic Lipid Nanoparticles Targeting Steroid Organs Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Nov, 2013 | Pubmed ID: 24071507 Physiologically Based Pharmacokinetic Modelling of Drug Penetration Across the Blood-brain Barrier--towards a Mechanistic IVIVE-based Approach The AAPS Journal. Oct, 2013 | Pubmed ID: 23784110 Respiratory Effects of Diazepam/methadone Combination in Rats: a Study Based on Concentration/effect Relationships Drug and Alcohol Dependence. Aug, 2013 | Pubmed ID: 23332448 Impact of Prescriber's Handwriting Style and Nurse's Duty Duration on the Prevalence of Transcription Errors in Public Hospitals Journal of Clinical Nursing. Feb, 2013 | Pubmed ID: 23228072 Hurdles with Using in Vitro Models to Predict Human Blood-brain Barrier Drug Permeability: a Special Focus on Transporters and Metabolizing Enzymes Current Drug Metabolism. Jan, 2013 | Pubmed ID: 23215812 Quantitative Targeted Absolute Proteomic Analysis of Transporters, Receptors and Junction Proteins for Validation of Human Cerebral Microvascular Endothelial Cell Line HCMEC/D3 As a Human Blood-brain Barrier Model Molecular Pharmaceutics. Jan, 2013 | Pubmed ID: 23137377 Sensory Impairment in Obese Patients? Sensitivity and Pain Detection Thresholds for Electrical Stimulation After Surgery-induced Weight Loss, and Comparison with a Nonobese Population The Clinical Journal of Pain. Jan, 2013 | Pubmed ID: 22688605 [Recent Advances in Quantitative Proteomics As a Sensitive Tool to Quantify Drug Transporters and Drug Metabolizing Enzymes at the Human Blood-brain Barrier] Biologie Aujourd'hui. 2012 | Pubmed ID: 23171840 Reduced Pupil Diameter in Volunteers on Stable Buprenorphine Maintenance Therapy with Telaprevir: a Drug-drug Interaction Involving P-glycoprotein at the Blood-brain Barrier? Antimicrobial Agents and Chemotherapy. Nov, 2012 | Pubmed ID: 23074230 Respiratory Toxicity of Buprenorphine Results from the Blockage of P-glycoprotein-mediated Efflux of Norbuprenorphine at the Blood-brain Barrier in Mice Critical Care Medicine. Dec, 2012 | Pubmed ID: 22975888 Development of a Physiologically Based Pharmacokinetic Model for the Rat Central Nervous System and Determination of an in Vitro-in Vivo Scaling Methodology for the Blood-brain Barrier Permeability of Two Transporter Substrates, Morphine and Oxycodone Journal of Pharmaceutical Sciences. Nov, 2012 | Pubmed ID: 22864977 Induction of P-glycoprotein and Bcrp at the Rat Blood-brain Barrier Following a Subchronic Morphine Treatment is Mediated Through NMDA/COX-2 Activation Journal of Neurochemistry. Nov, 2012 | Pubmed ID: 22845665 Expression and Induction by Dexamethasone of ABC Transporters and Nuclear Receptors in a Human T-lymphocyte Cell Line Journal of Chemotherapy (Florence, Italy). Feb, 2012 | Pubmed ID: 22546724 Etonorgestrel Concentrations in Morbidly Obese Women Following Roux-en-Y Gastric Bypass Surgery: Three Case Reports Contraception. Dec, 2011 | Pubmed ID: 22078197 Aryl Hydrocarbon Receptor-dependent Upregulation of Cyp1b1 by TCDD and Diesel Exhaust Particles in Rat Brain Microvessels Fluids and Barriers of the CNS. 2011 | Pubmed ID: 21867498 Opioid Transport by ATP-binding Cassette Transporters at the Blood-brain Barrier: Implications for Neuropsychopharmacology Current Pharmaceutical Design. 2011 | Pubmed ID: 21827411 Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels Molecular Pharmaceutics. Aug, 2011 | Pubmed ID: 21707071 How to Obtain DNA from Injection Drug Users? Clinical Chemistry and Laboratory Medicine : CCLM / FESCC. Aug, 2011 | Pubmed ID: 21679132 Electronic Prescribing Reduces Prescribing Error in Public Hospitals Journal of Clinical Nursing. Nov, 2011 | Pubmed ID: 21627699 Interplay of Drug Metabolizing CYP450 Enzymes and ABC Transporters in the Blood-brain Barrier Current Drug Metabolism. Oct, 2011 | Pubmed ID: 21623707 Validity of Leg-to-leg Bioelectrical Impedance Analysis to Estimate Body Fat in Obesity Obesity Surgery. Jul, 2011 | Pubmed ID: 20936394 ABC Transporters and Cytochromes P450 in the Human Central Nervous System: Influence on Brain Pharmacokinetics and Contribution to Neurodegenerative Disorders Expert Opinion on Drug Metabolism & Toxicology. Oct, 2010 | Pubmed ID: 20843279 Effect of Variations in the Amounts of P-glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 Along the Human Small Intestine on PBPK Models for Predicting Intestinal First Pass Molecular Pharmaceutics. Oct, 2010 | Pubmed ID: 20604570 Population Pharmacokinetics of 3,4-methylenedioxymethamphetamine and Main Metabolites in Rats Toxicological Sciences : an Official Journal of the Society of Toxicology. Mar, 2010 | Pubmed ID: 20008456 Mechanisms of Respiratory Insufficiency Induced by Methadone Overdose in Rats Addiction Biology. Jan, 2010 | Pubmed ID: 20002023 Interaction of Drugs of Abuse and Maintenance Treatments with Human P-glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). Aug, 2010 | Pubmed ID: 19887017 Influence of Development, HIV Infection, and Antiretroviral Therapies on the Gene Expression Profiles of ABC Transporters in Human Lymphocytes Journal of Clinical Pharmacology. Feb, 2010 | Pubmed ID: 19837908 Sprague-Dawley Rats Display Sex-linked Differences in the Pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA) and Its Metabolite 3,4-methylenedioxyamphetamine (MDA) Toxicology and Applied Pharmacology. Dec, 2009 | Pubmed ID: 19781562 Pharmacology of Morphine in Obese Patients: Clinical Implications Clinical Pharmacokinetics. 2009 | Pubmed ID: 19743886 Ibogaine Labeling with 99mTc-tricarbonyl: Synthesis and Transport at the Mouse Blood-brain Barrier Journal of Pharmaceutical Sciences. Dec, 2009 | Pubmed ID: 19492342 Xenobiotic-metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping As a Basis for Putative Roles in Cerebral Function Drug Metabolism and Disposition: the Biological Fate of Chemicals. Jul, 2009 | Pubmed ID: 19359404 Expression and Transcriptional Regulation of ABC Transporters and Cytochromes P450 in HCMEC/D3 Human Cerebral Microvascular Endothelial Cells Biochemical Pharmacology. Mar, 2009 | Pubmed ID: 19041851 ABC Transporters, Cytochromes P450 and Their Main Transcription Factors: Expression at the Human Blood-brain Barrier Journal of Neurochemistry. Dec, 2008 | Pubmed ID: 19094056 Effect of Chronic Exposure to Morphine on the Rat Blood-brain Barrier: Focus on the P-glycoprotein Journal of Neurochemistry. Nov, 2008 | Pubmed ID: 18761714 Buprenorphine Alters Desmethylflunitrazepam Disposition and Flunitrazepam Toxicity in Rats Toxicological Sciences : an Official Journal of the Society of Toxicology. Nov, 2008 | Pubmed ID: 18703559 Squalenoylation Favorably Modifies the in Vivo Pharmacokinetics and Biodistribution of Gemcitabine in Mice Drug Metabolism and Disposition: the Biological Fate of Chemicals. Aug, 2008 | Pubmed ID: 18474674 Sprague-Dawley Rats Display Metabolism-mediated Sex Differences in the Acute Toxicity of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) Toxicology and Applied Pharmacology. Jul, 2008 | Pubmed ID: 18358511 ABC Transporters and the Accumulation of Imatinib and Its Active Metabolite CGP74588 in Rat C6 Glioma Cells Pharmacological Research. Mar, 2008 | Pubmed ID: 18337118 A Functional in Vitro Model of Rat Blood-brain Barrier for Molecular Analysis of Efflux Transporters Brain Research. May, 2007 | Pubmed ID: 17434463 Case Report: Quantification of Methadone-induced Respiratory Depression Using Toxicokinetic/toxicodynamic Relationships Critical Care (London, England). 2007 | Pubmed ID: 17224045 Expression of Drug Transporters at the Blood-brain Barrier Using an Optimized Isolated Rat Brain Microvessel Strategy Brain Research. Feb, 2007 | Pubmed ID: 17196184 Is P-glycoprotein (ABCB1) a Phase 0 or a Phase 3 Colchicine Transporter Depending on Colchicine Exposure Conditions? Toxicology and Applied Pharmacology. Dec, 2006 | Pubmed ID: 16978677 Role of ABC Transporters in the Chemoresistance of Human Gliomas Current Cancer Drug Targets. Aug, 2006 | Pubmed ID: 16918310 Cerebral and Plasma Kinetics of a High Dose of Midazolam and Correlations with Its Respiratory Effects in Rats Toxicology Letters. Oct, 2005 | Pubmed ID: 15916873 P-glycoprotein (ABCB1) but Not Multidrug Resistance-associated Protein 1 (ABCC1) is Induced by Doxorubicin in Primary Cultures of Rat Astrocytes Journal of Neurochemistry. Nov, 2003 | Pubmed ID: 14622113 Molecular and Functional MDR1-Pgp and MRPs Expression in Human Glioblastoma Multiforme Cell Lines International Journal of Cancer. Journal International Du Cancer. Mar, 2002 | Pubmed ID: 11857404 Oprensning af musehjerne Fartøjer Anne-Cécile Boulay1,2,3, Bruno Saubaméa4, Xavier Declèves4, Martine Cohen-Salmon1,2,3 1Collège de France, Center for Interdisciplinary Research in Biology (CIRB), Centre National de la Recherche Scientifique CNRS, Unité Mixte de Recherche 7241, Institut National de la Santé et de la Recherche Médicale, 2Centre Interdisciplinaire de Recherche en Biologie, 3MEMOLIFE Laboratory of Excellence and Paris Science, Lettre Research University, 4Université Paris Descartes, Faculté de Pharmacie, Université Paris Diderot Neurociência
Oprensning af musehjerne Fartøjer Anne-Cécile Boulay1,2,3, Bruno Saubaméa4, Xavier Declèves4, Martine Cohen-Salmon1,2,3 1Collège de France, Center for Interdisciplinary Research in Biology (CIRB), Centre National de la Recherche Scientifique CNRS, Unité Mixte de Recherche 7241, Institut National de la Santé et de la Recherche Médicale, 2Centre Interdisciplinaire de Recherche en Biologie, 3MEMOLIFE Laboratory of Excellence and Paris Science, Lettre Research University, 4Université Paris Descartes, Faculté de Pharmacie, Université Paris Diderot Neurociência