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Imaging of Thyroid Hormone Action Indicator Mice to Assess Endocrine Disruption

October 6th, 2023
1,2, 1, *3, *1
1Laboratory of Molecular Cell Metabolism, Institute of Experimental Medicine, 2János Szentágothai PhD School of Neurosciences, Semmelweis University, 3Laboratory of Integrative Neuroendocrinology, Institute of Experimental Medicine
* These authors contributed equally

Summary
Automatic Translation

Thyroid Hormone Action Indicator musemodellen blev udviklet til at muliggøre vævsspecifik kvantificering af lokal skjoldbruskkirtelhormonvirkning ved hjælp af dets endogene reguleringsmaskineri. For nylig har det vist sig, at modellen er egnet til at karakterisere hormonforstyrrende kemikalier, der interagerer med skjoldbruskkirtelhormonøkonomien, både ved ex vivo og in vivo metoder.

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