Examining Tumor Cell Dissemination from Lung Metastases

July 07, 2023

使用光转换追踪肺转移瘤的肿瘤细胞播散

肺转移选择性光转化的手术方案

Madeline Friedman-DeLuca², Prachiben P. Patel², Burcu Karadal-Ferrena², Nicole D. Barth², Camille L. Duran², Xianjun Ye^2,3, Michael Papanicolaou⁴, John S. Condeelis^3,4,5,6,7, Maja H. Oktay^2,3,5,6,7, Lucia Borriello*^1,2,8, David Entenberg*^1,2,3,5,6

¹Department of Pathology,Albert Einstein College of Medicine/Montefiore Medical Center, ²Cancer Dormancy and Tumor Microenvironment Institute,Albert Einstein College of Medicine/Montefiore Medical Center, ³Gruss-Lipper Biophotonics Center,Albert Einstein College of Medicine/Montefiore Medical Center, ⁴Department of Cell Biology,Albert Einstein College of Medicine/Montefiore Medical Center, ⁵Montefiore Einstein Cancer Center,Albert Einstein College of Medicine/Montefiore Medical Center, ⁶Integrated Imaging Program for Cancer Research,Albert Einstein College of Medicine/Montefiore Medical Center, ⁷Department of Surgery,Albert Einstein College of Medicine/Montefiore Medical Center, ⁸Department of Cancer and Cellular Biology, Lewis Katz School of Medicine,Fox Chase Cancer Center

Summary

我们提出了一种研究肺转移肿瘤细胞再播散的方法，涉及肺转移的选择性光转化手术方案，然后鉴定三级器官中的红化肿瘤细胞。

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