The Affiliated Hospital of Qingdao University 1 article published in JoVE Biology Exploring Independent Effects of Follicle-Stimulating Hormone In Vivo in a Mouse Model Yanjing Guo1,2,3, Wei Li2,3, Yinghan Wang2 1The Affiliated Hospital of Qingdao University, 2Department of Anesthesiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 3Department of Anesthesiology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University Follicle-stimulating hormone (FSH) in various extragonadal tissues and organs is associated with the pathogenesis of multiple diseases. The ovariectomized and FSH-treated mouse model (OVF) can be used to explore the extragonadal actions of FSH.