CLIP - Childhood Leukemia Investigation Prague 1 article published in JoVE Cancer Research Assessment of the Metabolic Profile of Primary Leukemia Cells Katerina Hlozková1, Julia Starková1 1CLIP - Childhood Leukemia Investigation Prague, Second Faculty of Medicine, Laboratory of Molecular Genetics, Charles University, Prague Here we present a protocol for the isolation of leukemic cells from leukemia patients bone marrow and analysis of their metabolic state. Assessment of the metabolic profile of primary leukemia cells could help to better characterize the demand of primary cells and could lead up to more personalized medicine.