University of Arizona, Phoenix 1 article published in JoVE Biology Measurement of Endothelium-Dependent Vasorelaxation in the Mouse Thoracic Aorta Using Tensometric Small Volume Chamber Myography Brikena Gusek1, Robert Folk1, Tala Curry2, Mitra Esfandiarei1 1Department of Biomedical Sciences, College of Graduate Studies, Midwestern University, 2Department of Child Health, College of Medicine-Phoenix, University of Arizona, Phoenix The present protocol describes the concepts and technical application of the tensometric myograph technique using a multi-chamber myograph system in the experimental ex vivo assessment of mouse aortic endothelial function.