Environmental and Occupational Health Sciences Institute 1 article published in JoVE Developmental Biology Ex Vivo Perfusion of the Rodent Placenta Jeanine N. D'Errico1, Sara B. Fournier2, Phoebe A. Stapleton1,2 1Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, 2Environmental and Occupational Health Sciences Institute Here is presented a protocol of ex vivo maternal-fetal vascular perfusion to enable the administration of a test article into maternal vasculature and to evaluate placental transfer of xenobiotic particles or pharmacological agents in addition to alterations in placental physiology.