Roseman University of Health Sciences 1 article published in JoVE Medicine Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans Konstantinia Almpani1,2, Anna Adjei2, Denise K. Liberton1, Payal Verma1, Man Hung*2,3,4, Janice S. Lee*1 1National Institute of Dental and Craniofacial Research, 2College of Dental Medicine, Roseman University of Health Sciences, 3University of Utah School of Medicine, 4George E. Wahlen VA Medical Center Presented here is a detailed protocol for the conduction of three-dimensional cephalometric analysis with the use of human cone beam computed tomography scans.