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JoVE Journal Neuroscience
Mitochondrial Morphology Analysis by Immunohistochemistry on Paraffin-Embedded Brain Slices from α-Synuclein Pre-Formed Fibrils (PFF)-Injected Mice
 

Mitochondrial Morphology Analysis by Immunohistochemistry on Paraffin-Embedded Brain Slices from α-Synuclein Pre-Formed Fibrils (PFF)-Injected Mice

An In Situ Immunostaining Protocol for Parkinson's Disease Study

Article DOI: 10.3791/201001-v • 04:21 min • June 23rd, 2023
June 23rd, 2023 •
*1, *1, 1, 1, 1, 1, 1,2,3,4
1Achucarro Basque Center for Neuroscience, 2Department of Neuroscience, University of the Basque Country (UPV/EHU), 3Ikerbasque - Basque Foundation for Science, 4Oxford Parkinson’s Disease Centre and Department of Physiology, Anatomy and Genetics, University of Oxford
* These authors contributed equally

Tags

Histological Examination Mitochondrial Morphology Parkinson's Disease Model Mitochondria Energy Metabolism Neurons Mitochondrial Dysfunction Neurological Disorders Shape And Organization Of Mitochondrial Network Immunostaining VDAC1 Protein Image Analysis Neurodegenerative Disorders α-synuclein Aggregates Parkinson's Disease Pathology Substantia Nigra Pars Compacta Dopaminergic Neurons PS129 Lesions Mitochondrial Fragmentation
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