Waiting
Processando Login

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Immunology and Infection / Human In Vitro Suppression as Screening Tool for…
JoVE Journal
Immunology and Infection

É necessário ter uma assinatura JoVE para assistir este Faça login ou comece sua avaliação gratuita.

JoVE Journal Immunology and Infection
Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance
 
Click here for the English version

Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance

Article DOI: 10.3791/3071-v • 14:01 min • July 22nd, 2011
July 22nd, 2011 •
1, 2, 3
1Department of Pediatrics/Allergy, Medical College of Wisconsin, 2Flow Cytometry Core Facility, Medical College of Wisconsin, 3Max McGee National Research Center for Juvenile Diabetes and Human Molecular Genetics Center, Medical College of Wisconsin

Capítulos

Resumo
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

Tregs are potent suppressors of the immune system. There is a lack of unique surface markers to define them, hence, definitions of Tregs are primarily functional. Here we describe an optimized in vitro assay capable of identifying immune imbalance in subjects at risk to develop T1D.

Tags

Human In Vitro Suppression Screening Tool Recognition Early State Immune Imbalance Regulatory T Cells Tregs Immune Tolerance Self-antigens Infection Surface Marker Proliferation Function Effector T Cells In Vitro Assays Cross-sectional Studies Autoimmune Diseases Type 1 Diabetes-T1D Laboratories Responder T Cells Stimulation Treg:responder Ratios Antigen-presenting Cells (APC) Variability Comparison Between Studies Standardized Suppression Assay Healthy Subjects Autoimmune Destruction Of Pancreatic β-cells
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter