This content is Free Access.
Chapters
- 00:05Title
- 01:03Real Time Cell Analyzer (RTCA)-based Dose Range Finding (DRF)
- 04:26Preparation for Measuring Toxicological Effects by High-content Screening (HCS)
- 06:27Cytotoxicity Assay
- 09:19Results: Representative Results for 1-Aminonaphtalene
- 10:26Conclusion
The objective of the study was to assess the biological impact of 15 cigarette smoke constituents using a combination of an impedance-based real time cell analyzer and a high-content screening (HCS)-based platform for toxicological assessment in vitro. This study provides information on effective doses, toxicity and modes of action of the tested compounds.
