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Ferric Chloride-induced Murine Thrombosis Models
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JoVE Journal Medicina
Ferric Chloride-induced Murine Thrombosis Models

Ferric Chloride-induced Murine Thrombosis Models

DOI:
10.3791/54479-v

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10:37 min

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September 05, 2016

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, ,
1Department of Cellular and Molecular Medicine,Lerner Research Institute, Cleveland Clinic, 2Department of Molecular Medicine,Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, 3Department of Pharmacology,Case Western Reserve University, 4Department of Biomedical Engineering,Case Western Reserve University

Capítulos

  • 00:05Título
  • 01:11Carotid Artery Thrombosis Preparation
  • 05:48Real Time Carotid Artery Imaging
  • 07:31Results: Representative Studies using the FeCl3-induced Thrombosis
  • 09:03Conclusion

Summary

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Tadução automática

We report a refined procedure of the ferric chloride (FeCl3)-induced thrombosis models on carotid and mesenteric artery as well as vein, characterized efficiently using intravital microscopy to monitor time to occlusive thrombi formation.

Tags

Ferric Chloride-induced ThrombosisMouse Carotid Artery ModelIntravital MicroscopyPlatelet ActivationThrombosisAnticoagulantAntiplatelet DrugsPathophysiology Of ThrombosisNovel DrugsTargeted NanomedicineFur RemovalSurgical IncisionJugular Vein DissectionRhodamine 6G Solution

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