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JoVE Journal Bioengineering
A Facile and Eco-friendly Route to Fabricate Poly(Lactic Acid) Scaffolds with Graded Pore Size
 

A Facile and Eco-friendly Route to Fabricate Poly(Lactic Acid) Scaffolds with Graded Pore Size

Article DOI: 10.3791/54595-v • 13:46 min • October 17th, 2016
October 17th, 2016 •
1, 1, 1, 1, 1, 1, 1
1Department of civil, environmental, aerospace, and materials engineering (DICAM), RU INSTM, University of Palermo

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In this work, poly(lactic acid)/polyethylene glycol (PLA/PEG) scaffolds were prepared by using a combination of melt mixing and selective leaching. The method herein discussed permitted to develop three-layer scaffolds by highly controlling both porosity and pore size. The mechanical properties were also evaluated in a physiological environment.

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Keywords: Poly(lactic Acid) Scaffolds Graded Pore Size Tissue Engineering Melt Mixing Compression Molding Salt Leaching Eco-friendly Morphological Analysis Mechanical Behavior Processing-structure-property Relationship
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