Journal
/
Pesquisa do Câncer
/
纳米颗粒对荷瘤小鼠药相结合的样品提取及同时色谱定量分析
JoVE Journal
Pesquisa do Câncer
É necessária uma assinatura da JoVE para visualizar este conteúdo.  Faça login ou comece sua avaliação gratuita.
JoVE Journal Pesquisa do Câncer
Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice
Please note that all translations are automatically generated. Click here for the English version.

纳米颗粒对荷瘤小鼠药相结合的样品提取及同时色谱定量分析

DOI:
10.3791/56159-v

•

08:57 min

•

October 05, 2017

•

, , , , , , ,
1Department of Pharmaceutical Sciences,University of Toronto, 2Departments of Medical Biophysics and Radiation Oncology, University of Toronto, Ontario Cancer Institute,University Health Network

Capítulos

  • 00:05Título
  • 01:20Biological Sample Preparation
  • 03:35HPLC Instrumentation and Operation Parameters
  • 04:50Analysis of Samples
  • 05:46Results: Drug Combination Delivery of Doxorubicin and Mitomycin C in Nanoparticles
  • 07:43Conclusion

Summary

Tadução automática

Tadução automática

该协议描述了一个高效和方便的分析过程中的样品提取和同时测定多药, 阿霉素 (DOX), 丝裂霉 C (MMC) 和心脏毒性 DOX 代谢物, doxorubicinol (DOXol), 在生物样品的临床前乳腺癌模型治疗的纳米颗粒制剂的协同药物组合。

Tags

DoxorubicinMitomycin CDoxorubicinolNanoparticlesTumorHPLCSimultaneous QuantitationSample PreparationExtractionInternal Standard

Article

Embed

ADICIONAR À PLAYLIST

Usage Statistics

Vídeos Relacionados

check_url/pt/56159?article_type=v

利用RNA测序来检测新剪接变异体在相关耐药<em>体外</em>癌症模型
check_url/pt/56159?article_type=v

结肠-26癌荷瘤小鼠为癌症恶病质的研究模型
check_url/pt/56159?article_type=v

测定急性髓系白血病可测残留病和白血病干细胞的骨髓标本和过程综合协议
check_url/pt/56159?article_type=v

c-fos 和 dusp1 在癌基因依赖性中的作用评价方法
check_url/pt/56159?article_type=v

抗肿瘤药物对抗癌抗体疗效的潜力: 用组合指数方程检测抗体-药物协同作用
check_url/pt/56159?article_type=v

将操纵的肿瘤相关中性粒细胞转移到肿瘤携带小鼠中,以研究其血管生成潜力在Vivo
check_url/pt/56159?article_type=v

在斑马鱼肿瘤异种移植物中宿主血管反应的Vivo成像和定量
check_url/pt/56159?article_type=v

聚酐IL-1α纳米颗粒 体内抗肿瘤 活性评价
check_url/pt/56159?article_type=v

Exploring Mitochondrial Energy Metabolism of Single 3D Microtissue Spheroids Using Extracellular Flux Analysis
check_url/pt/56159?article_type=v

基于同步成像和流式细胞术检测治疗诱导的衰老癌细胞中的多种荧光衰老标志物

Read Article