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A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis
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Neurociência
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JoVE Journal Neurociência
A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

DOI:
10.3791/56723-v

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06:19 min

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January 07, 2018

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, , , ,
1Department of Regenerative Medicine and Tissue Engineering,National Cerebral and Cardiovascular Center, 2Institut de Neurosciences de la Timone, CNRS,Aix Marseille Université

Capítulos

  • 00:05Título
  • 00:46Mild Intrauterine Hypoperfusion (MIUH)
  • 05:12Results: Representative Effects of MIUH on IN Utero and Post-birth Pup Development
  • 05:51Conclusion

Summary

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Mild intrauterine hypoperfusion was produced by artery stenosis with metal microcoils wrapped around the uterine and ovarian arteries in rats at embryonic day 17. This procedure produced prenatal hypoperfusion and intrauterine growth restriction.

Tags

Rat ModelIntrauterine HypoperfusionMicrocoil StenosisFetal Brain InjuryNeural DevelopmentUterine ArteryOvarian ArteryPlacenta4-0 Silk SutureGold-coated Steel Microcoil

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