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Partial Bile Duct Ligation in the Mouse
 

Partial Bile Duct Ligation in the Mouse: A Controlled Model of Localized Obstructive Cholestasis

Article DOI: 10.3791/56930-v • 04:38 min • March 28th, 2018
March 28th, 2018 •
1,2, 2, 2, 3, 4,5, 3,4,5,6
1Department of Surgery, Jichi Medical University, 2Department of Surgery, University of Pittsburgh School of Medicine, 3Department of Pediatrics, University of Pittsburgh School of Medicine, 4Department of Pathology, University of Pittsburgh School of Medicine, 5Pittsburgh Liver Research Center, University of Pittsburgh, 6McGowan Institute for Regenerative Medicine, University of Pittsburgh

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Here, we present partial bile duct ligation as a surgical model of liver injury and regeneration in rodents.

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Bile Duct Ligation Localized Obstructive Cholestasis Surgical Intervention Hepatology Liver Regeneration Ligated Experimental Lobe Unligated Control Lobe Dr. Toshimasa Nakao Post-doc Transplant Surgery Laboratory C57 Black 6 Mouse Anesthesia Abdominal Region Surgical Microscope Limbs Sterile Swabs Povidone-iodine Ethanol Midline Incision Xiphoid Pubis Micro Retractor Abdominal Cavity Mosquito Forceps Soft Clay Sterilized PBS
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