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Intracerebroventricular Treatment with Resiniferatoxin and Pain Tests in Mice
 

Intracerebroventricular Treatment with Resiniferatoxin and Pain Tests in Mice

Article DOI: 10.3791/57570-v 06:04 min September 2nd, 2020
September 2nd, 2020

Capítulos

Resumo

The transient receptor potential vanilloid type 1 (TRPV1) in the supraspinal region has been suggested to play some roles in the brain function. Described here is a protocol for intracerebroventricular injection of resiniferatoxin for supraspinal TRPV1 desensitization in mice. Procedures for some pain tests are also presented.

Tags

Keywords: Intracerebroventricular Resiniferatoxin TRPV1 Desensitization Anesthesia Subcutaneous Injection Paw Withdrawal Tail Pressure Test Nociception Mouse Model Neuropharmalogical Research
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