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颅内 Subarachnoidal 感染对猪链球菌生物膜在小鼠感染模型中作用的研究

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Imunologia e Infecção

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JoVE Journal Imunologia e Infecção

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model

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颅内 Subarachnoidal 感染对猪链球菌生物膜在小鼠感染模型中作用的研究

DOI:

10.3791/57658-v

•

07:26 min

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July 01, 2018

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Shouming Zhang^2,3, Xueping Gao^2,3, Genhui Xiao^2,3,4, Chengping Lu^2,3, Huochun Yao^2,3, Hongjie Fan^2,3,5, Zongfu Wu^2,3

¹College of Veterinary Medicine,Nanjing Agricultural University, ²Key Lab of Animal Bacteriology,Ministry of Agriculture, ³OIE Reference Lab for Swine Streptococcosis, ⁴School of Medicine,Tsinghua University, ⁵Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses

Capítulos

00:04Título
00:46Preparation of Bacteria
02:50Detecting the mRNA Expression of TLR2 and Cytokines in Brain Tissue
05:30Results: S. suis Biofilms Contribute to Induction of Meningitis
06:51Conclusion

Summary

Tadução automática

本文描述了小鼠颅内 subarachnoidal 感染的途径, 研究了生物膜在猪链球菌脑膜炎中的作用。这种感染模型也适用于研究其他细菌性脑膜炎的发病机制和新药对细菌性脑膜炎的疗效。

Tags

Keywords: Streptococcus Suis Biofilms Meningitis Mouse Infection Model Intracranial Subarachnoidal Infection Planktonic Cells Biofilm State Cells RNA Extraction

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