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Using 22C3 Anti-PD-L1 Antibody Concentrate on Biopsy and Cytology Samples from Non-small Cell Lung Cancer Patients
JoVE Journal
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JoVE Journal Pesquisa do Câncer
Using 22C3 Anti-PD-L1 Antibody Concentrate on Biopsy and Cytology Samples from Non-small Cell Lung Cancer Patients
DOI:

07:43 min

September 25, 2018

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Capítulos

  • 00:04Título
  • 01:13Preparation of Tumor Tissue Samples
  • 01:53Preparation of Cytology Samples
  • 02:56PD-L1 Staining Assay
  • 04:27Interpretation of the PD-L1 Staining
  • 05:08Results: Analysis of the PD-L1 Staining
  • 06:23Conclusion

Summary

Tadução automática

To expand the ability of laboratories worldwide to assess the eligibility of patients with lung cancer for treatment with pembrolizumab, in a reliable and reproducible manner, we developed an assay that uses the 22C3 antibody concentrate on a widely available immunohistochemical autostainer, for both biopsy and cytology specimens.

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