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宿主病原学反应及疫苗效果评价

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Imunologia e Infecção

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JoVE Journal Imunologia e Infecção

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

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宿主病原学反应及疫苗效果评价

DOI:

10.3791/58930-v

•

08:52 min

•

February 22, 2019

•

Kyle Caution, Kacy Yount, Rajendar Deora², Purnima Dubey

¹Department of Microbial Infection & Immunity,The Ohio State University, ²Department of Microbiology,The Ohio State University

Capítulos

00:04Título
00:31Immunization and Intranasal Infection
01:58Tissue Harvest
05:49Lung Processing
07:04Results: Representative Host-Pathogen Response and Vaccine Efficacy Analyses
07:56Conclusion

Summary

Tadução automática

在这里, 我们提出了一个优雅的协议, 在体内评估疫苗的有效性和宿主免疫反应。该协议可适用于研究病毒、细菌或寄生虫病原体的疫苗模型。

Tags

Keywords: Host-pathogen Response Vaccine Efficacy Mouse Model Immunization Bacterial Infection Organ Harvest Spleen RPMI Fetal Bovine Serum

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