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以血管内炎组织调节为重点, 利用肠系膜孤立动脉评价血管张力
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Biologia
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JoVE Journal Biologia
Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues
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以血管内炎组织调节为重点, 利用肠系膜孤立动脉评价血管张力

DOI:
10.3791/59688-v

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08:41 min

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June 03, 2019

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, , , , , , ,
1The State Key Laboratory of Pharmaceutical Biotechnology and the Department of Pharmacology and Pharmacy,University of Hong Kong

Capítulos

  • 00:04Título
  • 01:17Normalization to Determine the Optimal Initial Tension
  • 03:43Phenylephrine-induced Contractions
  • 05:52Results: Optimal Initial Tensions and Output Recordings of the Vasoconstrictor Responses to Phenylephrine in Mesenteric Arteries With or Without Surrounding PVAT
  • 07:34Conclusion

Summary

Tadução automática

Tadução automática

该协议描述了使用线状成像来评估从小鼠分离肠系膜动脉的神经间等距张力, 特别考虑的是内皮细胞和血管周围脂肪组织释放的因素的调节。

Tags

Vascular ToneMesenteric ArteriesIsometric ConditionVascular ResponsivenessHypertensionCardiovascular ComplicationsMyographNormalizationPassive StretchWall TensionActive ForcePotassium Chloride

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